87239-94-9

Basic information

• Product Name: Benzeneacetic acid, 2-(dithiocarboxy)hydrazide, monopotassium salt
• CAS NO: 87239-94-9
• Molecular Formula: C9H10N2OS2.K
• Molecular Weight: 264.414
• Mol File: 87239-94-9.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: Benzeneacetic acid, 2-(dithiocarboxy)hydrazide, monopotassium salt(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetic acid, 2-(dithiocarboxy)hydrazide, monopotassium salt(87239-94-9)
• EPA Substance Registry System: Benzeneacetic acid, 2-(dithiocarboxy)hydrazide, monopotassium salt(87239-94-9)

Safety Data

• Hazardous Substances Data: 87239-94-9(Hazardous Substances Data)

Upstream product

• 103-79-7 1-phenyl-acetone 
• 101-41-7 benzeneacetic acid methyl ester 
• 103-82-2 phenylacetic acid 
• 101-97-3 Ethyl 2-phenylethanoate 
• 75-15-0 carbon disulfide 
• 937-39-3 2-phenylacetylhydrazine 

Downstream Products

• 183244-46-4 N-(3-benzyl-5-mercapto-[1,2,4]triazol-4-yl)-isonicotinamide 
• 29546-25-6 2-mercapto-5-benzyl-1,3,4-thiadiazole 
• 708292-90-4 3-benzyl-6-(3-bromophenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 
• 708995-56-6 3-benzyl-6-(4-bromophenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 
• 1213786-79-8 3-benzyl-6-(1H-2-indolylmethyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 
• 708997-85-7 3-benzyl-6-(1-naphthylmethyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 
• 96134-14-4 C₁₅H₁₄N₄S 
• 29546-25-6 5-benzyl-3H-[1,3,4]thiadiazole-2-thione 
• 13373-10-9 4-amino-2,4-dihydro-5-(phenylmethyl)-3H-1,2,4-triazole-3-thione 
• 96134-19-9 N-(3-Benzyl-5-thioxo-1,5-dihydro-[1,2,4]triazol-4-yl)-benzamide 
• 111828-06-9 (4-amino-5-benzyl-4H-1,2,4-triazol-3-ylsulphanyl)-methylenenitrile 
• 111828-17-2 (4-Amino-5-benzyl-4H-[1,2,4]triazol-3-ylsulfanyl)-acetic acid hydrazide 
• 111828-12-7 (4-Amino-5-benzyl-4H-[1,2,4]triazol-3-ylsulfanyl)-acetic acid methyl ester 
• 111827-92-0 N-(3-Benzyl-5-thioxo-1,5-dihydro-[1,2,4]triazol-4-yl)-acetamide 

Relevant articles and documents

Efficient formation of C–S bond using heterocyclic thiones and arynes

Phenylthio heterocyclic compounds are widely used because of their diverse biological activities and medicinal prospects. Here, a facile method was reported. An arylation of 1,3,4-oxa(thia)diazol-2-thiones reacting with arynes to build C(aryl)-S bonds in the presence of CsF had good yields and excellent selectivity. The reaction was completed in short time without using expensive reagents and catalysts. Present reaction system is an efficient procedure to process phenylthio heterocyclic compounds and reveals a sustainable method and better application prospects in future organic synthesis.

Synthesis of Novel 1,2,4-Triazole-3-thione Derivatives as Influenza Neuraminidase Inhibitors

A series of 1,2,4-triazole-3-thione derivatives (6a–6t) were synthesized and evaluated against influenza viruses (H1N1) neuraminidase (NA) in vitro. Eighteen compounds exhibited inhibitory potency with IC50 values ranging from 14.68?±?0.49 to 39.85?±?4.23?μg/mL. Among them, compounds 6e and 6h showed significant inhibitory activity with IC50 values of 14.97?±?0.70 and 14.68?±?0.49?μg/mL, respectively. Structure activity relationships were established. Molecular docking studies were performed to understand the binding interaction between active compounds and NA.

Antibacterial drug for targeted therapy of staphylococcal infection by synergizing with antibiotic as well as synthesis method and application of antibacterial drug

The invention designs and synthesizes a novel antibacterial drug ASC for staphylococcus aureus based on a beta-lactam ring of a parent nucleus structure of beta-lactam antibiotic molecules, wherein the ASC is an antibacterial reagent and is also a broad-spectrum inhibitor of beta-lactam antibiotic drug-resistant target protein metal beta-lactamase; the ASC can synergize with three kinds of 7 to 8antibiotics such as beta-lactams, aminoglycosides and tetracyclines to carry out targeted therapy on the staphylococcal infection. The vitality of the antibiotics is increased by 4 to 128 times by combining with 1 [mu]g/ml dosage of ASC.