70951-79-0Relevant academic research and scientific papers
Kinetics and reactivity of substituted anilines with 2-chloro-5-nitropyridine in dimethyl sulfoxide and dimethyl formamide
El-Bardan, Ali A.,El-Subruiti, Gehan M.,El-Hegazy, Fatma El-Zahraa M.,Hamed, Ezzat A.
, p. 645 - 650 (2007/10/03)
The kinetics of the reaction of substituted anilines with 2-chloro-5-nitropyridine were studied in dimethyl sulfoxide (DMSO) and dimethyl formamide (DMF) at different amine concentrations and temperatures in the range 45-60°C. In both solvents the reaction was not a base-catalyzed one. A plot of ΔH# versus ΔS# for the reaction in DMSO and DMF gave good straight lines with isokinetic temperatures 128°C and 105°C, respectively. Good linear relationships were obtained from the plots of log k1 against σ° values at all temperatures with negative ρ values (- 1.63 to - 1.28 in DMSO) and (- 1.26 to -0.90 in DMF).
