70958-24-6Relevant academic research and scientific papers
Synthesis of N-Sulfonyl Pyrazoles Through Cyclization Reactions of Sulfonyl Hydrazines with Enaminones Promoted by p-TSA
Zhang, Qiaohe,Hu, Biao,Zhao, Yuxuan,Zhao, Siyun,Wang, Yanqin,Zhang, Biao,Yan, Shengjiao,Yu, Fuchao
, p. 1154 - 1159 (2020/02/27)
A strategy for the rapid synthesis of 3-substituted N-sulfonyl pyrazoles via p-TSA-promoted cyclization reactions of sulfonyl hydrazines with N,N-dimethyl enaminones has been developed. This method achieves both the formation of pyrazole ring and the cont
Method for synthesis of substituted 1-sulfonyl-1H-pyrazole
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Paragraph 0077; 0078; 0079; 0080; 0081, (2017/10/07)
The invention discloses a method for synthesis of substituted 1-sulfonyl-1H-pyrazole, and aims to provide a method for synthesis of 1-sulfonyl-1H-pyrazole, the method has the advantages of simple and easily available starting materials, high yield and easy operation, the method is characterized in that sulfonyl hydrazone, N, N-dimethylmalononitrile and a Lewis acid catalyst are in turn added into an organic solvent for heating refluxing reaction to obtain the substituted 1-sulfonyl-1H-pyrazole, and the method belongs to the organic synthesis technical field.
Zinc-promoted cyclization of tosylhydrazones and 2-(dimethylamino)malononitrile: An efficient strategy for the synthesis of substituted 1-tosyl-1: H -pyrazoles
Zhang, Bang-Hong,Lei, Lin-Sheng,Liu, Si-Zhan,Mou, Xue-Qing,Liu, Wei-Ting,Wang, Shao-Hua,Wang, Jie,Bao, Wen,Zhang, Kun
supporting information, p. 8545 - 8548 (2017/08/04)
A Zn(OTf)2-promoted cyclization reaction of tosylhydrazones with 2-(dimethylamino)malononitrile has been successfully developed providing an efficient strategy for the synthesis of substituted 1-tosyl-1H-pyrazoles.
Novel generation and cycloaddition reactivity of N-phenylsulfonylbenzonitrilimine via thermal decomposition of N-(phenylsulfonyl)benzohydrazonoyl chloride
Sasaki, Tadashi,Eguchi, Shoji,Tanaka, Yumo
, p. 1565 - 1569 (2007/10/02)
Thermal decomposition of N(phenylsulfonyl)-benzohydrazonoyl chloride (1) in refluxing toluene generated N-phenylsulfonylbenzonitrilimine (2) which gave 1,3-dipolar cycloadducts with ethyl (4a) and methyl acrylate (4b), acrylonitrile (4c), styrene (4d), norbornene (4e), and norbornadiene (4f). The reactions with 4a-d, 2 afforded regiospecifically 5-R substituted pyrazolines 5a-d in lower yields. The raction of 2 with 4e gave only exo adduct 5e, while the reaction with 4f gave both exo- (5fx) and endo adducts (5fn) as well as their retro-Diels-Alder product 6.
