709640-99-3Relevant academic research and scientific papers
Cascade synthesis of benzofuran derivatives via laccase oxidation-Michael addition
Witayakran, Suteera,Gelbaum, Leslie,Ragauskas, Arthur J.
, p. 10958 - 10962 (2007)
The cascade synthesis of benzofuran derivatives was conducted from the reaction of catechols and 1,3-dicarbonyl compounds via oxidation-Michael addition in the presence of laccase and Sc(OTf)3/SDS. This reaction was carried out under air at room temperature in aqueous medium, and provided benzofuran products in moderate to good yields. In addition, this reaction system showed recyclability.
One-pot laccase-catalysed synthesis of 5,6-dihydroxylated benzo[b]furans and catechol derivatives, and their anticancer activity
Wellington, Kevin W.,Qwebani-Ogunleye, Tozama,Kolesnikova, Natasha I.,Brady, Dean,De Koning, Charles B.
, p. 266 - 277 (2013/06/27)
A commercial laccase, Suberase from Novozymes, was used to catalyse the synthesis of 5,6-dihydroxylated benzo[b]furans and catechol derivatives. The yields were, in some cases, similar to or better than that obtained by other enzymatic, chemical or electr
Cocatalytic enzyme system for the Michael addition reaction of in-situ-generated ortho-quinones
Witayakran, Suteera,Ragauskas, Arthur J.
experimental part, p. 358 - 363 (2009/07/04)
A laccase-lipase cocatalytic system was used to catalyze the domino reaction between catechols and nucleophilic reagents including 1,3-dicarbonyl compounds and aromatic amines in aqueous medium at room temperature. Lipase acted as a catalyst for Michael a
