70978-05-1

Upstream product

• 100-39-0 benzyl bromide 
• 100245-10-1 2-Benzyloxy-1-methoxy-3-nitro-benzene 

Downstream Products

• 70978-02-8 1-benzyl-1H-tetrazole-5-carboxylic acid 2-benzyloxy-3-methoxy-anilide 
• 220034-72-0 2-Benzyloxy-6-iodo-3-methoxy-phenylamine 
• 70977-51-4 N-(2-hydroxy-3-methoxyphenyl)-1H-tetrazole-5-carboxamide 
• 220034-67-3 N-tosyldiscorhabdin C 
• 220034-62-8 {2-[7-Benzyloxy-6-methoxy-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-ethyl}-carbamic acid tert-butyl ester 
• 220034-66-2 C₂₅H₂₁N₃O₄S 
• 220034-64-0 7-(3,5-dibromo-4-hydroxyphenethylamino)-1-tosyl-3,4-dihydropyrrolo[4,3,2-de]quinolin-8(1H)-one 
• 220034-65-1 7-[2-(3-Bromo-4-hydroxy-phenyl)-ethylamino]-1-(toluene-4-sulfonyl)-3,4-dihydro-1H-pyrrolo[4,3,2-de]quinolin-8-one 
• 220034-59-3 7-(4-hydroxyphenethylamino)-1-tosyl-3,4-dihydropyrrolo[4,3,2-de]quinolin-8(1H)-one 
• 220034-63-9 {2-[7-Hydroxy-6-methoxy-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-ethyl}-carbamic acid tert-butyl ester 
• 220034-73-1 [2-(7-Benzyloxy-6-methoxy-1H-indol-3-yl)-ethyl]-carbamic acid tert-butyl ester 
• 220034-60-6 (E)-4-(2-Benzyloxy-6-iodo-3-methoxy-phenylamino)-but-2-enenitrile 
• 220034-61-7 (7-Benzyloxy-6-methoxy-1H-indol-3-yl)-acetonitrile 
• 161156-09-8 {2-[6-Methoxy-4,7-dioxo-1-(toluene-4-sulfonyl)-4,7-dihydro-1H-indol-3-yl]-ethyl}-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

A biomimetic approach to the discorhabdin alkaloids: Total syntheses of discorhabdins C and E and dethiadiscorhabdin D

The characteristic spirodienone structure of the discorhabdin alkaloids is readily formed by reaction of the tyramine-substituted indoloquinonimines 26, 35, and 36 with cupric chloride, triethylamine, and oxygen. This cyclization provides a possibly biomimetic route to discorhabdins C and E (41 and 42). The unbrominated spirodienone 40 reacts with hydrogen over Pd/C to give enone 46. Bromination at the α position gives a mixture of bromoenones that undergo smooth conversion to dethiadiscorhabdin D (4) upon treatment with basic alumina.