70988-26-0Relevant academic research and scientific papers
New Synthesis of 1,1-Substituted Hydrazines by Alkylation of N-Acyl- or N-alkyloxycarbonylaminophthalimide Using the Mitsunobu Protocol
Brosse, Nicolas,Pinto, Maria-Fatima,Jamart-Gregoire, Brigitte
, p. 4370 - 4374 (2007/10/03)
N-acyl- and N-alkoxycarbonylaminophthalimides are prepared using a convenient reaction and are efficiently used as acid partners in Mitsunobu reaction. This reaction allows them to be alkylated by primary, secondary or benzyl groups. Comparison of the reactivities and pKa values of these N-substituted aminophthalimides suggest that the success of the Mitsunobu reaction in this case seems to be governed more by steric than by electronic effects. A final dephthaloylation step results in an efficient method for the preparation of 1,1-substituted hydrazines.
Synthesis and Spectra of Some Phthalimido Derivatives
Sadek, Mohamed M. El,Essawi, Mohyi M. El,Baky, Samy A. Abdel
, p. 257 - 259 (2007/10/02)
The reactions of some aroylhydrazines and amino derivatives of heterocyclic compounds with phthalic anhydride were investigated.Dehydration of the prepared carboxybenzoyl derivatives afforded the corresponding phthalimido products.The structures were confirmed by IR, proton NMR, and mass spectra.
