70988-59-9

Upstream product

• 70988-58-8 3,4'-bis-(2-methoxycarbonyl-ethyl)-4,3'-bis-methoxycarbonylmethyl-1H,1'H-5,5'-methanediyl-bis-pyrrole-2-carboxylic acid 2-benzyl ester 
• 70988-57-7 benzyl 5'-t.butyloxycarbonyl-4,3'-di(2-methoxycarbonylethyl)-3,4'-bismethoxycarbonylmethyl-2,2'-methylenedipyrrole-5-carboxylate 
• 207974-96-7 1-Benzyloxycarbonyl-2,7-bis(2-methoxycarbonylethyl)-3,8-bis(methoxycarbonylmethyl)-9-(2,2,2-tribromoethoxycarbonyl)dipyrromethane 
• 104705-81-9 5-Acetoxymethyl-4-(2-methoxycarbonyl-ethyl)-3-methoxycarbonylmethyl-1H-pyrrole-2-carboxylic acid 2,2,2-tribromo-ethyl ester 
• 50622-60-1 3-(2-methoxycarbonyl-ethyl)-4-methoxycarbonylmethyl-pyrrole-2-carboxylic acid benzyl ester 

Downstream Products

• 71015-84-4 benzyl 5'-formyl-4,3'-di(2-methoxycarbonylethyl)-3,4'-bismethoxy-carbonylmethyl-2,2'-methylenedipyrrole-5-carboxylate 
• 71861-60-4 3,8,13,18-tetra-(2-carboxyethyl)-2,7,12,17-tetrakiscarboxymethyl-1-hydroxymethylbilane 
• 1976-85-8 uroporphyrinogen III 
• 1867-62-5 uroporphyrinogen I 

Relevant academic research and scientific papers

Biosynthesis of porphyrins and related macrocycles. Part 48. The rearrangement of 2H-pyrroles (pyrrolenines) related to the proposed spiro-intermediate for porphyrin biosynthesis

It is proposed that the biosynthesis of uroporphyrinogen III 3, the parent precursor of the natural porphyrins, chlorins and corrins, involves a 2H-pyrrole (pyrrolenine) 2 as a key intermediate. Model pyrrolenines have now been used to show that (a) pyrro

Biosynthesis of Porphyrins and Related Macrocycles. Part 18. Proof by Spectroscopy and Synthesis that Unrearranged Hydroxymethylbilane is the Product from Deaminase and the Substrate for Cosynthetase in the Biosynthesis of Uropophyrinogen-III

When the enzyme deaminase acts alone on porphobilinogen, it releases a tarnsient intermediate into the medium which is unaffected by further treatment with a large excess of deaminase.The intermediate undergoes rapid ring-closure chemically (t1/2/su