710-14-5

Usage

Chemical Properties

clear colorless liquid

InChI:InChI=1/C10H18O3/c1-2-6-12-10(5-1)13-8-9-4-3-7-11-9/h9-10H,1-8H2/t9-,10+/m0/s1

Upstream product

• 97-99-4 Tetrahydrofurfuryl alcohol 
• 110-87-2 3,4-dihydro-2H-pyran 

Downstream Products

• 637-64-9 tetrahydrofurfuryl acetate 
• 97-99-4 Tetrahydrofurfuryl alcohol 

Relevant academic research and scientific papers

AI(OTf)3 - A highly efficient catalyst for the tetrahydropyranylation of alcohols under solvent-free conditions

A simple and highly efficient method has been developed for the tetrahydropyranylation of alcohols by their reaction with 3,4-dihydro-2H-pyran (DHP) using a catalytic amount (0.01-1 mol%) of aluminium triflate under solvent-free conditions. The effect of various factors like temperature, amount of the catalyst, and molar ratio of substrates on the reaction conditions has also been studied. The comparative study of tetrahydropyranylation of benzyl alcohol using various catalysts including some reported ones shows the efficiency of this catalyst.

Bronsted acidic ionic liquids: Fast, mild, and efficient catalysts for solvent-free tetrahydropyranylation of alcohols

Bronsted acidic ionic liquids as efficient and reusable catalysts for the protection of alcohols as tetrahydropyranyl (THP) ethers under solvent-free conditions at room temperature was investigated. Good to excellent yields were obtained at a faster rate over [BMIm][HSO4] or [BMIm][H2PO4]. Copyright Taylor & Francis, Inc.

A simple and efficient tetrahydropyranylation using N-bromosuccinamide

Tetrahydropyranylation of hydroxyl groups of alcohols and phenols has been achieved easily and efficiently using N-bromosuccinamide at room temperature.

Phosphorus pentoxide as an efficient catalyst for the tetrahydropyranylation of alcohols under solvent-free conditions

A facile and efficient method for the preparation of tetrahydropyranyl ethers from alcohols is improved in solvent-free media. These reactions are catalyzed by P2O5 and afford various tetrahydropyranyl ethers in shorter reaction time, with good to excellent yields (75-95%) at room temperature. This method is also compatible with substrates containing acid-sensitive functional groups.

Facile Tetrahydropyranylation of Alcohols and Phenols Using Anhydrous Calcium Chloride under Mild and Neutral Conditions

Treatment of 3,4-dihydro-2H-pyran with various alcohols and phenols in the presence of a catalytic amount of anhydrous calcium chloride in dichloromethane furnished tetrahydropyranyl ethers under almost neutral conditions.

Simple protocol for synthesis and cleavage of tetrahydropyranyl ethers using FeSO4 as an inexpensive catalyst

Protection and deprotection of alcohols and phenols as tetrahydropyranyl ethers (THP ethers) using anhydrous FeSO4 under microwave irradiation without solvent is carried out.

Protection of alcohols and phenols with dihydropyran and detetrahydropyranylation by ZrCl4

Alcohols and Phenols are protected efficiently with dihydropyran(DHP) in the presence of catalytic amounts of zirconium tetrachloridein dichloromethane. Deprotection of THP-ethers is also afforded in a methanolic solution at room temperature.

Zirconium sulfophenyl phosphonate as a heterogeneous catalyst in tetrahydropyranylation of alcohols and phenols

Zirconium Sulfophenyl Phosphonate Zr(O3PCH3)(1.2)(O3PC6- InSO3H)(0.8) was found to be an efficient heterogeneous catalyst for the tetrahydropyranylation of alcohols and phenols.

Mild and efficient tetrahydropyranylation and deprotection of alcohols catalyzed by heteropoly acids

A simple, mild and effective method to form 2-tetrahydropyranyl ethers of alcohols and phenol and the removal of this protective group in the presence of heteropoly acids as catalysts are described.