71002-09-0

Usage

Uses

Antirheumatic.

InChI:InChI=1/C17H12ClFN2O2/c18-12-3-1-11(2-4-12)15-10-21(20-16(15)9-17(22)23)14-7-5-13(19)6-8-14/h1-8,10H,9H2,(H,22,23)

Upstream product

• 81321-74-6 4-(4-Chlorphenyl)-1-(4-fluorphenyl)-pyrazol-3-acetonitril 
• 81321-33-7 (E)-N-[2-(4-Chlorophenyl)ethenyl]morpholine 
• 77442-96-7 <4-(4-Chlorphenyl)-1-(4-fluorphenyl)-3-pyrazolyl>-methylketon 
• 81321-57-5 <4-(4-Chlorphenyl)-1-(4-fluorphenyl)-3-pyrazolyl>-methanol 
• 81321-66-6 3-Brommethyl-4-(4-chlorphenyl)-1-(4-fluorphenyl)-pyrazol 
• 140-53-4 p-chlorobenzyl cyanide 
• 81321-40-6 4-(4-Chlorphenyl)-1-(4-fluorphenyl)-5-morpholino-4,5-dihydro-pyrazol-3-carbonsaeure-ethylester 
• 77442-95-6 1-[4-(4-Chloro-phenyl)-1-(4-fluoro-phenyl)-5-morpholin-4-yl-4,5-dihydro-1H-pyrazol-3-yl]-ethanone 
• 81321-45-1 4-(4-Chlorphenyl)-1-(4-fluorphenyl)-pyrazol-3-carbonsaeure-ethylester 
• 77442-97-8 2-[4-(4-Chloro-phenyl)-1-(4-fluoro-phenyl)-1H-pyrazol-3-yl]-1-morpholin-4-yl-ethanethione 

Downstream Products

• 90934-29-5 4-(4-Chlorphenyl)-1-(4-fluorphenyl)-pyrazol-3-essigsaeure(11β,17-dihydroxy-3,20-dioxo-4-pregnen-21-yl)-ester 
• 87267-81-0 4-<4-(4-Chlorphenyl)-1-(4-fluorphenyl)-3-pyrazolylacetyl>-morpholin 
• 87267-80-9 4-(4-Chlorphenyl)-1-(4-fluorphenyl)-pyrazol-3-essigsaeure-(2-dimethylaminoethyl)-ester 
• 87267-85-4 4-(4-Chlorphenyl)-1-(4-fluorphenyl)-pyrazol-3-acetoxyessigsaeure 
• 87267-83-2 N-<4-(4-Chlorphenyl)-1-(4-fluorphenyl)-3-pyrazolylacetyl>-glycin 
• 87267-84-3 4-(4-Chlorphenyl)-1-(4-fluorphenyl)-pyrazol-3-acetohydroxamsaeure 
• 87267-82-1 <4-(4-Chlorphenyl)-1-(4-fluorphenyl)-3-pyrazolyl>-acetamid 
• 86768-16-3 5-Chlor-4-(4-chlorphenyl)-1-(4-fluorphenyl)-pyrazol-3-essigsaeure 
• 87267-68-3 4-(4-Chlorphenyl)-1-(4-fluorphenyl)-pyrazol-3-essigsaeurechlorid 
• 87267-79-6 2-<4-(4-Chlorphenyl)-1-(4-fluorphenyl)-3-pyrazolyl>-ethanol 
• 87267-69-4 4-(4-Chlorphenyl)-1-(4-fluorphenyl)-pyrazol-3-acetoxyessigsaeure-tert.butylester 
• 87267-78-5 4-(4-Chlorphenyl)-1-(4-fluorphenyl)-pyrazol-3-essigsaeure-ethylester 

Relevant academic research and scientific papers

Process for the preparation of (1,4-diaryl-pyrazol-3-yl)-acetic acids

(1,4-Diaryl-purazol-3-yl)-acetic acids of the formula STR1 wherein Ar and Ar', which can be the same or different, represents a phenyl group optionally substituted with 1 or 3 halogen atoms, C1 -C4 alkyl or C1 -C4 alkoxy groups, are prepared by reacting β-styryl amines with compounds of formula ClCO-CH2 -A (wherein A represents a CN, COOR or CONR1 R2 group, R being an alkyl, benzyl or benzohydryl group and R1 and R2 being H or an alkyl, benzyl or benzohydryl group).

Process for the preparation of (1,4-diaryl-pyrazol-3-yl)-acetic acids

(1,4-diaryl-pyrazol-3-yl)-acetic acids of the formula I wherein Ar and Ar?, which can be the same or differen, represen a phenyl group optionally substituted with 1 to 3 halogen atoms, C1-C4 alkyl or C1-C4 alkoxy groups, are prepared by reacting β-styryl amines with compounds of formula ClCO-CH2-A (wherein A represent a CN, COOR or CONR1R2 group, R being an alkyl, benzyl or benzohydryl group and R1and R2 being H or an alkyl, benzyl or benzohydryl group).