7101-04-4

Usage

Uses

Used in Organic Chemistry:
(1Z)-1-phenyl-2-piperidin-1-ylethanone oxime is used as a reagent for the synthesis of various organic compounds. Its unique chemical properties make it a valuable component in the creation of new molecules and materials.
Used in Pharmacology:
(1Z)-1-phenyl-2-piperidin-1-ylethanone oxime is recognized for its potential pharmacological properties. It is considered a potential drug candidate for the treatment of various diseases, making it a promising option for further research and development in the medical field.
Used in Research and Development:
(1Z)-1-phenyl-2-piperidin-1-ylethanone oxime is widely used in research and development due to its unique chemical properties and potential applications in various industries. Its versatility allows scientists and researchers to explore its capabilities and discover new uses for this chemical compound.

Upstream product

• 4641-62-7 1-phenyl-2-piperidino-ethanone; hydrochloride 
• 110-89-4 piperidine 
• 40814-66-2 (Z)-2-chloro-1-phenylethan-1-one oxime 
• 17082-13-2 α-bromoacetophenone oxime 
• 100-42-5 styrene 
• 100-75-4 N-nitrosopiperidine 
• 779-52-2 1-phenyl-2-piperidin-1-yl-ethanone 

Relevant academic research and scientific papers

Visible-Light-Induced Photoaddition of N-Nitrosoalkylamines to Alkenes: One-Pot Tandem Approach to 1,2-Diamination of Alkenes from Secondary Amines

The generation of aminium radical cation species from N-nitrosoamines is disclosed for the first time through visible-light excitation at 453 nm. The developed visible-light-promoted photoaddition reaction of N-nitrosoamines to alkenes was combined with the o-NQ-catalyzed aerobic oxidation protocol of amines to telescope the direct handling of harmful N-nitroso compounds, where the desired α-amino oxime derivatives were obtained in a one-pot tandem N-nitrosation and photoaddition sequence.

Synthesis and Study of New Clathrochelates with 1-Phenyl-2-(1'-Piperidinyl) Ethanone Oxime Ligand

The synthesis and characterization of new complex compounds of [M(L-H)X2], [ML(L-H)]X and [M(L-H)2] types (M = Co, Ni, Cu, X = Cl, CH3COO) and L = 1-phenyl-2-(1'-piperidinyl) ethanone oxime is presented. In reactions of [ML(L-H)]X (M = Ni, Cu) with Lewis acids like TiCl4 and SnCl4 semiclathrochelates of [M(L-H)2M'Cl2] type (M' = Ti, Sn) were obtained and characterized (electronic, FT-IR, RPE, NMR spectra, conductivity measurements, as well as TD-analysis). Such complexes should be potential oxygen molecular carriers.

Ring cleavage of 2-phenyl-3,5,6,7,8,8a-hexahydro-imidazo[1,2-a]pyridin-1-oxide by substitution

The cyclic α-amino nitrone 2 reacts with Grignard reagents yielding the ring opened 2-substituted piperidine oximes 7 and 8, but not the substituted cyclic hydroxylamines of type 4, a formerly supposed. The structures of 7 and 8 were proved by unequivocal

STEREOCHEMISTRY OF α-AMINOACETOPHENONE OXIMES STUDY OF SOLVENT EFFECTS

The aminolysis of Z-α-halogenoacetophenone oximes results in different mixtures of E- and Z-α-aminoacetophenone oximes depending on the solvent used.Assignment of configuration can be achieved by 13C NMR spectroscopy even if only one isomer is available using a strong solvent dependence of the methylene chemical shift in the case of the Z-isomers.This effect is due to the presence of different conformations in the solvents chloroform and dimethyl sulfoxide.Together with a study by vapor pressure osmometry the results provide an unambiguous proof of intramolecular hydrogen bonding of Z-α-aminoacetophenone oximes in chloroform.