71027-02-6 Usage
Uses
Used in Medicinal Chemistry Research:
4,4,4-Trifluorocrotonic acid is used as a research compound for the development of new pharmaceuticals. Its unique structure and properties make it a valuable building block in the synthesis of various drug molecules.
Used in Organic Synthesis:
4,4,4-Trifluorocrotonic acid is used as a reagent in organic synthesis, particularly in the preparation of fluorinated compounds. Its presence in the molecule can impart specific chemical and physical properties to the final product, making it a useful intermediate in the synthesis of complex organic molecules.
Used in Fluorine Chemistry:
4,4,4-Trifluorocrotonic acid is used as a starting material in fluorine chemistry, where the introduction of fluorine atoms can significantly alter the reactivity and properties of organic compounds. This makes it an important precursor in the synthesis of fluorinated compounds with potential applications in various fields, such as pharmaceuticals, agrochemicals, and materials science.
Used in Material Science:
4,4,4-Trifluorocrotonic acid is used as a monomer in the polymerization process to create new materials with specific properties. The incorporation of fluorine atoms in the polymer backbone can lead to materials with improved thermal stability, chemical resistance, and other desirable characteristics, making them suitable for various applications in the material science field.
Check Digit Verification of cas no
The CAS Registry Mumber 71027-02-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,0,2 and 7 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 71027-02:
(7*7)+(6*1)+(5*0)+(4*2)+(3*7)+(2*0)+(1*2)=86
86 % 10 = 6
So 71027-02-6 is a valid CAS Registry Number.
InChI:InChI=1/C4H3F3O2/c5-4(6,7)2-1-3(8)9/h1-2H,(H,8,9)/b2-1+
71027-02-6Relevant articles and documents
PRODUCTION METHOD OF FLUORINE-CONTAINING UNSATURATED CARBOXYLIC ACID
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Paragraph 0293-0302, (2021/02/11)
PROBLEM TO BE SOLVED: To provide a production method of a compound of formula (4), that is, a fluorine-containing unsaturated carboxylic acid, which is industrially preferable, economical, and environmentally friendly. SOLUTION: A production method of a compound of formula (4) includes subjecting a compound of formula (3) to a reaction in the presence of a base (here Rf is a 1-4C perfluoroalkyl). SELECTED DRAWING: None COPYRIGHT: (C)2021,JPO&INPIT
BICYCLIC JAK INHIBITORS AND USES THEREOF
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Paragraph 000308, (2020/10/20)
Provided herein are compounds of Formulas (I), (II), (III), and (IV) and subformulas thereof, wherein the variables are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I), (II), (III), or (IV) and methods of using the compounds, e.g., in the treatment of immune disorders, inflammatory disorders, and cancer.
The effect of fluoromethyl groups on the diastereoselectivity in the electrophilic alkylation
Tamura, Kenji,Yamazaki, Takashi,Kitazume, Tomoya,Kubota, Toshio
, p. 918 - 930 (2007/10/03)
The effect of fluoromethyl groups on the diastereoselectivity in the electrophilic alkylation is described. In particular, the electrophilic alkylation of enolates with a trifluoromethyl group was proceeded with highly diastereofacial selectivity based on the steric and/or electrostatic effect of substituent with strong electron withdrawing.
