710279-21-3Relevant academic research and scientific papers
Facile copper-mediated activation of the N-H bond and the oxidative cleavage of the C2-C3 bond in 1H-2-phenyl-3-hydroxy-4-oxoquinoline
Czaun, Miklos,Speier, Gabor,Parkanyi, Laszlo
, p. 1004 - 1005 (2004)
The reaction of 1H-2-phenyl-3-hydroxy-4-oxoquinoline (PhquinH2; 1) with metallic copper leads to CuII(PhquinH)2 while in the presence of PPh3 to Cu12Cu II(Phquin)2(PPh3)4. In the presence of tmeda and O2 ring cleavage occurs to give CuII(tmeda) (PhquinH)(N-baa). Both reactions represent a mild N-H activation and an oxidative C-C bond scission.
