71028-59-6Relevant academic research and scientific papers
Polyenolates of unsaturated carboxylic acids in synthesis. Synthesis of unsaturated α-amino acids and γ-hydrazino acids
Aurell,Gil,Martinez,Parra,Tortajada,Mestres
, p. 1833 - 1839 (2007/10/02)
Regioselective reaction of lithium diene- and triene-diolates 1 and 2 with o-diphenylphosphinyl hydroxylamine affords unsaturated α-amino acids 3 and 4. Addition to DEAD leads selectively to γ-hydrazino unsaturated acids 5 and 6.
Ueber einen neuartigen synthetischen Zugang zu β,γ-ungesaettigten α-Aminocarbonsaeuren
Heinzer, Franz,Bellus, Daniel
, p. 2279 - 2297 (2007/10/02)
A versatile new synthetic pathway for the preparation of β,γ-unsaturated α-amino acids (1) is presented.Cu(I)-catalyzed addition of ethyl isocyanoacetate (2) to α-chloro carbonyl compounds (3) gives 5-chloroalkyl-2-oxazolin-4-carboxylates (4) in high yiel
