80744-75-8Relevant academic research and scientific papers
Ueber einen neuartigen synthetischen Zugang zu β,γ-ungesaettigten α-Aminocarbonsaeuren
Heinzer, Franz,Bellus, Daniel
, p. 2279 - 2297 (1981)
A versatile new synthetic pathway for the preparation of β,γ-unsaturated α-amino acids (1) is presented.Cu(I)-catalyzed addition of ethyl isocyanoacetate (2) to α-chloro carbonyl compounds (3) gives 5-chloroalkyl-2-oxazolin-4-carboxylates (4) in high yiel
