710322-80-8

Upstream product

• 300356-14-3 (R)-2-(3-chloro-4-(methylsulfonyl)phenyl)-3-cyclopentylpropanoic acid 
• 620596-94-3 2-amino-5-ethenylpyrazine 

Downstream Products

• 710321-76-9 (R)-2-(3-Chloro-4-methanesulfonyl-phenyl)-3-cyclopentyl-N-[5-((S)-1,2-dihydroxy-ethyl)-pyrazin-2-yl]-propionamide 
• 710321-77-0 2(R)-(3-chloro-4-methanesulfonyl-phenyl)-3-cyclopentyl-N-[5-1(R),2-dihydroxy-ethyl-pyrazin-2-yl]-propionamide 
• 710321-87-2 2(R)-(3-chloro-4-methanesulfonyl-phenyl)-3-cyclopentyl-N-[5-(1 (S), 2-dihydroxy-ethyl)-pyrazin-2-yl]-propionamide 

Relevant academic research and scientific papers

5-SUBSTITUTED-PYRAZINE OR PYRIDINE GLUCOKINASE ACTIVATORS

The present invention provides a compound according to formula (I) where the substituent designations are provided in the specification. Pharmaceutical compositions comprising a compound according to formula (I) are also provided, said compounds being glucokinase activators which are useful in the treatment of type II diabetes.