7107-59-7

Usage

Uses

Used in Cosmetic and Personal Care Industry:
Benzyl (4-hydroxyphenyl)carbamate is used as a sunscreen agent and UV absorber for its ability to absorb UV light and convert it into harmless heat. This property makes it an effective ingredient in skincare products designed to protect the skin from the harmful effects of sun exposure, such as sunburn, premature aging, and skin cancer.
Used in Sunscreen Products:
Benzyl (4-hydroxyphenyl)carbamate is used as an active ingredient in sunscreen products to provide broad-spectrum protection against both UVA and UVB rays. Its inclusion in sunscreen formulations helps to prevent skin damage and reduce the risk of skin cancer caused by excessive sun exposure.
Used in Skincare Formulations:
In addition to sunscreens, benzyl (4-hydroxyphenyl)carbamate is also used in various skincare formulations, such as moisturizers, serums, and creams, to offer additional UV protection and support the skin's overall health. Its presence in these products helps to maintain the skin's natural barrier function and prevent environmental damage.
Used in European Union and Other Regions:
Benzyl (4-hydroxyphenyl)carbamate has been approved for use in the European Union and other regions, ensuring its availability and safety for consumers seeking effective sun protection in their skincare products. This approval highlights the compound's compliance with stringent safety and efficacy standards, further reinforcing its value in the cosmetic and personal care industry.
It is important to follow safety guidelines and use products containing benzyl (4-hydroxyphenyl)carbamate as directed to avoid any potential adverse effects. By incorporating benzyl (4-hydroxyphenyl)carbamate into sunscreen and skincare formulations, manufacturers can offer consumers effective protection against the harmful effects of UV radiation, promoting healthier and more resilient skin.

Upstream product

• 123-30-8 4-amino-phenol 
• 501-53-1 benzyl chloroformate 
• 100-02-7 4-nitro-phenol 
• 20443-91-8 2-(4-nitrophenoxy)tetrahydropyran 
• 104-57-4 benzyl formate 
• 54840-15-2 4-N-tert-butoxycarbonylaminophenol 
• 16801-63-1 benzyl N-(4-oxocyclohexyl)carbamate 
• 174359-47-8 p-tetrahydropyran-2-yloxy-N-(benzyloxycarbonyl)aminobenzene 
• 97389-23-6 4-[(2-tetrahydropyranyloxy)methyl]aniline 

Downstream Products

• 110876-77-2 [4-(2-piperidino-ethoxy)-phenyl]-carbamic acid benzyl ester 
• 174359-49-0 (R)-2-tert-Butoxycarbonylamino-propionic acid 4-benzyloxycarbonylamino-phenyl ester 
• 174359-51-4 (2-tert-Butoxycarbonylamino-acetylamino)-acetic acid 4-benzyloxycarbonylamino-phenyl ester 
• 174359-50-3 (S)-2-tert-Butoxycarbonylamino-3-phenyl-propionic acid 4-benzyloxycarbonylamino-phenyl ester 
• 174359-53-6 ((S)-2-tert-Butoxycarbonylamino-propionylamino)-acetic acid 4-benzyloxycarbonylamino-phenyl ester 
• 174359-54-7 ((R)-2-tert-Butoxycarbonylamino-propionylamino)-acetic acid 4-benzyloxycarbonylamino-phenyl ester 
• 515163-30-1 allyl 4-N-(benzyloxycarbonyl)aminophenyl ether 
• 123-30-8 4-amino-phenol 

Relevant academic research and scientific papers

Positioning of an unprecedented 1,5-oxaza spiroquinone scaffold into SMYD2 inhibitors in epigenetic space

Lysine methyltransferases are important regulators of epigenetic signaling and are emerging as a novel drug target for drug discovery. This work demonstrates the positioning of novel 1,5-oxaza spiroquinone scaffold into selective SET and MYND domain-conta

PIFA-Promoted, Solvent-Controlled Selective Functionalization of C(sp2)-H or C(sp3)-H: Nitration via C-N Bond Cleavage of CH3NO2, Cyanation, or Oxygenation in Water

A novel nitration (via C(sp3)-N breaking/C(sp2)-N formation with CH3NO2) mediated by [bis(trifluoroacetoxy)iodo]benzene (PIFA) is described. The NO2 transfer from CH3NO2 to the aromatic group of the substrate is possible with careful selection of the solvent, NaX, and oxidant. In addition, the solvent-controlled C(sp2)-H functionalization can shift to an α-C(sp3)-H functionalization (cyanation or oxygenation) of the α-C(sp3)-H of cyclic amines.

One stone two birds: Cobalt-catalyzed in situ generation of isocyanates and benzyl alcohols for the synthesis of N-aryl carbamates

An efficient method for the synthesis of N-aryl carbamates from N-Boc-protected amines has been developed. The cobalt-catalyzed in situ generation of isocyanates from N-Boc-protected amines and benzyl alcohols from benzyl formates has been achieved for the first time, which in turn furnished the corresponding benzyl carbamates in moderate to high yields. The reaction was catalyzed by CoI2 with tris-(4-dimethylaminophenyl)-phosphine as the ligand and zinc powder as the reductant. The developed reaction conditions were found to be compatible for aromatic amines with both electron-donating and -withdrawing substituents.

NOVEL SPIROQUINONE DERIVATIVE COMPOUND, PRODUCTION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NEUROLOGICAL DISORDERS WHICH CONTAINS SAME AS ACTIVE INGREDIENT

The present invention relates to a novel spiroquinone derivative compound, a production method thereof, and a pharmaceutical composition for preventing or treating neurological disorders which contains the compound as an active ingredient, and it has been

Bazedoxifene-scaffold-based mimetics of solomonsterols A and B as novel pregnane x receptor antagonists

Pregnane X receptor (PXR), a member of the NR1I nuclear receptor family, acts as a xenobiotic sensor and a paramount transcriptional regulator of drug-metabolizing enzymes and transporters. The overexpression of PXR in various cancer cells indicates the importance of PXR as a drug target for countering multidrug resistance in anticancer treatments. We describe the discovery of novel bazedoxifene-scaffold-based PXR antagonists inspired by the marine sulfated steroids solomonsterol A and B as natural leads. A luciferase reporter assay on a PXR-transfected HepG2 cell line identified compounds 19-24 as promising PXR antagonists. Further structure-activity relationship studies of the most active PXR antagonist from the series (compound 20, IC50 = 11 μM) revealed the importance of hydroxyl groups as hydrogen-bond donors for PXR antagonistic activity. PXR antagonists 20 and 24 (IC50 = 14 μM), in addition to the downregulation of PXR expression, exhibited inhibition of PXR-induced CYP3A4 expression, which illustrates their potential to suppress PXR-regulated phase-I drug metabolism.

One-pot catalysis of dehydrogenation of cyclohexanones to phenols and oxidative Heck coupling: Expedient synthesis of coumarins

One-pot reactions leading to highly functionalized coumarins have been developed via a Pd(ii)-catalyzed dehydrogenation-oxidative Heck-cyclization process.

A facile protocol for N-Cbz protection of amines in PEG-600

An efficient and eco-friendly protocol for the chemoselective N-benzyloxycarbonylation of amines was described. The reaction of amines with benzyl chloroformate (Cbz-Cl) in the presence of PEG-600 at room temperature afforded the corresponding N-Cbz derivatives in excellent yields. The method is applicable to the N-Cbz protection of aliphatic (acyclic and cyclic) and aromatic amines.

Synthesis of a β-cyclodextrin derivate and its molecular recognition behavior on modified glassy carbon electrode by diazotization

A novel β-cyclodextrin (β-CD) derivative containing mono-phenylamino (MPA-β-CD) was newly synthesized by classical Mitsunobu reaction in good yield, and its structure has been confirmed by 1H NMR, 13C NMR and electrospray ionization

A mild and efficient chemoselective: N-benzyloxycarbonylation of amines using TBAB a catalyst under solvent-free conditions

We describe a mild and efficient method for the chemoselective N-benzyloxycarbonylation of amines by treatment amines and aminoesters with benzyloxycarbonyl chloride (Cbz-Cl) in the presence of TBAB under solvent-free in excellent yields. The method is ge

FUSED HETEROCYCLIC DERIVATIVES AND USE THEREOF

The present invention provides a fused heterocyclic derivative having a strong kinase inhibitory activity and use thereof. The present invention relates to a compound represented by the formula wherein each symbol is as defined in the present specificatio