71087-75-7Relevant academic research and scientific papers
Iron powder and tin/tin chloride as new reducing agents of Meerwein arylation reaction with unexpected recycling to anilines
Abdelwahab, Ahmed B.,El-Sawy, Eslam R.,Kirsch, Gilbert
supporting information, p. 526 - 538 (2020/01/08)
Simple and rapid route for Meerwein arylation reaction using iron powder or a mixture of tin/tin chloride has been developed. In the presence of iron powder, different aryl diazonium salts reacted with methyl vinyl ketone, acrylates, and isopropenyl acetate. Production of oximes was detected as the main product with acrylates or in a mixture with β-aryl methyl ketones in the case of methyl vinyl ketone. The in situ produced HNO2 from an excess of NaNO2/HCl was trapped by alkyl aryl radical to form oximes in the E configuration form. The presence of tin/tin chloride mixture in the reaction of the aryl diazonium salts with methyl vinyl ketone produced Michael products along with β-aryl methyl ketones. The predicted α-aryl methyl ketones from the reaction of isopropenyl acetate with the diazotized anilines were obtained using iron or tin/tin chloride mixture.
Preparation, reduction chimique et electrochimique d'α-nitrostyrylcetones - synthese d'heterocycles azotes
Marcot, Bernard,Rabaron, Alain,Viel, Claude,Bellec, Christian,Deswarte, Stephane,Maitte, Pierre
, p. 1224 - 1234 (2007/10/02)
Nitration of styryl ketones with nitrogen peroxide leads to the corresponding α-nitroethylenic ketones in good yield.However, the presence of methoxy groups involves a nitration on the aromatic nucleus.LiAlH4 reduction of α-nitrostyrylketones yields the c
