710949-40-9Relevant academic research and scientific papers
Photochemically initiated oxidative carbon-carbon bond-cleavage reactivity in chlorodiketonate NiII complexes
Allpress, Caleb J.,Arif, Atta M.,Houghton, Dylan T.,Berreau, Lisa M.
, p. 14962 - 14973 (2011)
Three mononuclear NiII complexes containing a 2-chloro-1,3-diketonate ligand and supported by the 6-Ph2TPA chelate, as well as analogues that lack the 2-chloro substituent on the β-diketonate ligand, have been prepared and characterized. Upon irradiation at 350 nm under aerobic conditions, complexes containing the 2-chloro-substituted ligands undergo reactions to generate products resulting from oxidative cleavage, α-cleavage, and radical-derived reactions involving the 2-chloro-1,3-diketonate ligand. Mechanistic studies suggest that the oxidative cleavage reactivity, which leads to the production of carboxylic acids, is a result of the formation of superoxide, which occurs through reaction of reduced nickel complexes with O2. The presence of the 2-chloro substituent was found to be a prerequisite for oxidative carbon-carbon bond-cleavage reactivity, as complexes lacking this functional group did not undergo these reactions following prolonged irradiation. The approach toward investigating the oxidative reactivity of metal β-diketonate species outlined herein has yielded results of relevance to the proposed mechanistic pathways of metalloenzyme-catalyzed β-diketonate oxidative cleavage reactions.
Reactions of 1,3-diaryl-2-chloropropane-1,3-diones with nucleophiles - Cyanide-induced retro-Claisen-Claisen condensation
Roshchupkina, Galina I.,Gatilov, Yury V.,Rybalova, Tatyana V.,Reznikov, Vladimir A.
, p. 1765 - 1773 (2007/10/03)
Treatment of some 1,3-diaryl-2-chloropropane-1,3-diones, acyclic chloro-substituted enaminones and β-oxo esters with nucleophiles was shown to proceed easily with the formation, at least in the first stage, of formal nucleophilic substitution products. Treatment of enaminones and β-oxo esters with azide and cyanide ions proceeds with the preservation of the skeleton, whereas chloro-substituted diaroylmethanes undergo retro-Claisen-Claisen condensation reactions in the course of the reaction with cyanide. Dibenzoylchloromethane reacts with azide and cyanide ions with fragmentation of the molecule and subsequent reassembly, resulting in benzoylated benzaldehyde cyanohydrin and a 1,3-oxathiol derivative, respectively. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.
