71095-20-0

Usage

Uses

Used in Pharmaceutical Research:
2-AMINO-1-(2-BROMOPHENYL)ETHANOL is utilized as a building block in pharmaceutical research for its ability to contribute to the development of new drug candidates. Its unique structure allows it to be a valuable component in the synthesis of various medicinal compounds.
Used in Organic Synthesis:
In the field of organic synthesis, 2-AMINO-1-(2-BROMOPHENYL)ETHANOL serves as a key intermediate, facilitating the creation of a wide range of organic compounds due to its reactive functional groups.
Used in Neuroprotective Agent Synthesis:
2-AMINO-1-(2-BROMOPHENYL)ETHANOL is used as a precursor in the synthesis of neuroprotective agents, highlighting its potential role in the development of treatments aimed at protecting the nervous system from damage or disease.
Used in Drug Development:
As a ligand, 2-AMINO-1-(2-BROMOPHENYL)ETHANOL is instrumental in the development of potential drug candidates, where its specific interactions with biological targets can lead to the discovery of new therapeutic agents.
Used in Antitumor Research:
2-AMINO-1-(2-BROMOPHENYL)ETHANOL has been investigated for its potential antitumor properties, suggesting that it may contribute to the development of cancer treatments by targeting and inhibiting tumor growth.
Used in Antimicrobial Applications:
2-AMINO-1-(2-BROMOPHENYL)ETHANOL has also been studied for its antimicrobial properties, indicating its potential use in the development of new antibiotics or antifungal agents to combat microbial infections.

InChI:InChI=1/C8H10BrNO/c9-7-4-2-1-3-6(7)8(11)5-10/h1-4,8,11H,5,10H2

Upstream product

• 7677-24-9 trimethylsilyl cyanide 
• 6630-33-7 ortho-bromobenzaldehyde 
• 95-46-5 2-methylphenyl bromide 
• 35849-08-2 1-bromo-2-(dibromomethyl)benzene 
• 2039-88-5 2-bromostyrene 
• 52923-21-4 2-(2-bromophenyl)-2-hydroxyacetonitrile 

Downstream Products

• 496790-63-7 2-(2-bromophenyl)-2-methoxyethyl carbamic acid tert-butyl ester 
• 337966-19-5 benzhydrylidene-[2-(2-bromo-phenyl)-2-methoxy-ethyl]-amine 
• 337966-09-3 N-(1-phenylbenzyl)-3-methoxyindoline 
• 337966-03-7 2-(ortho-bromophenyl)-2-methoxyethylamine 
• 496790-62-6 2-(2-bromophenyl)-2-hydroxyethyl carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

4,5,6,7-TETRAHYDROTHIENO[2,3-C]PYRIDINE SUMO INHIBITORS AND USES THEREOF

The present invention relates to compounds and compositions capable of acting as inhibitors of small ubiquitin-like modifier (SUMO) family of proteins. The compounds and compositions may be used in the treatment of cancer. There are disclosed, inter alia,

Direct catalytic synthesis of unprotected 2-amino-1-phenylethanols from alkenes by using iron(II) phthalocyanine

Aryl-substituted amino alcohols are privileged scaffolds in medicinal chemistry and natural products. Herein, we report that an exceptionally simple and inexpensive FeII complex efficiently catalyzes the direct transformation of simple alkenes into unprotected amino alcohols in good yield and perfect regioselectivity. This new catalytic method was applied in the expedient synthesis of bioactive molecules and could be extended to aminoetherification.

Free radical-mediated aryl amination and its use in a convergent [3 + 2] strategy for enantioselective indoline α-amino acid synthesis

The scope of aryl radical additions to the nitrogen of azomethines is described. Aryl, trifluoromethyl alkyl, and α,β-unsaturated ketimines engage in regioselective aryl-nitrogen bond formation via 5-exo cyclizations of an aryl radical to azomethine nitrogen. Selectivity for carbon-nitrogen over carbon-carbon bond formation is generally high (>95:5) and competes only with direct aryl radical reduction by stannane (0-10%). α-Ketoimines are a promising new class of carbon radical acceptors for which no competitive aryl radical reduction is observed. The reaction conditions are pH-neutral and are therefore among the mildest methods available for amination of an aromatic ring. The ketimines examined did not suffer from competitive reduction by stannane, offering an advantage over the use of diazo and azide functional groups as nitrogen sources for carbon radicals. The free radical-mediated aryl amination was sequenced with the O'Donnell phase transfer-catalyzed enantioselective alkylation strategy of glycinyl imine to provide either enantiomer of indoline α-amino acids with high ee. These new constrained phenyl alanine derivatives are now readily available for evaluation across a variety of applications.