71098-29-8Relevant academic research and scientific papers
A Novel Vinyl Anion Equivalent. An Extremely Short Synthesis of 2-Substituted 2-Cycloalkenones and Prostaglandin Key Intermediates via Destannylselenenylation
Kusuda, Shinya,Watanabe, Yoshihiko,Ueno, Yoshio,Toru, Takeshi
, p. 3145 - 3152 (2007/10/02)
The preparation of a novel vinyl anion equivalent and a new destannylselenenylation procedure are described.The conjugate addition of (tributylstannyl)lithium to 2-(phenylseleno)-2-cycloalkenones, followed by the trapping of the resulting enolates with al
5,6-Dihydro analogues of prostaglandin I2
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, (2008/06/13)
Derivatives of prostaglandin I2 characterized by the generic structural formulae, STR1 are useful for inhibiting platelet aggregation or gastric acidity in individuals for whom such therapy is indicated. In the preceding structural formulae: B
Bicycloalkyl derivatives of prostaglandins
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, (2008/06/13)
Novel bicycloalkyl analogues or derivatives of prostaglandin A, E and F are useful modifiers of smooth muscle activity. The compounds have valuable pharmacological properties as platelet antiaggregating agents and gastric antisecretory agents. The compounds are also valuable pharmacological agents for increasing femoral blood flow and decreasing blood pressure and heart rate.
