711002-74-3

Basic information

• Product Name: 1-N-Cbz-3-aminopiperidine
• Synonyms: DL-3-AMINO-1-N-CBZ-PIPERIDINE;3-AMINOPIPERIDINE, N1-CBZ PROTECTED;3-AMINO-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER;3-AMINO-1-N-CBZ-PIPERIDINE;1-N-CBZ-3-AMINOPIPERIDINE;3-Aminopiperidine, N1-CBZ protected 97%;3-Amino-1-benzyloxycarbonylpiperidine;3-AMINO-1-BENZYLOXYCARBONYL-PIPERIDINE X HCL >98%
• CAS NO: 711002-74-3
• Molecular Formula: C₁₃H₁₈N₂O₂
• Molecular Weight: 234.29
• Product Categories: Amines;Pyrans, Piperidines &Piperazines;Piperaizine;Pyrans, Piperidines & Piperazines
• Mol File: 711002-74-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 168-170°C
• Boiling Point: 367.2 °C at 760 mmHg
• Flash Point: 175.9 °C
• Appearance: /
• Density: 1.151 g/cm³
• Vapor Pressure: 1.38E-05mmHg at 25°C
• Refractive Index: 1.558
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 10.33±0.20(Predicted)
• CAS DataBase Reference: 1-N-Cbz-3-aminopiperidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-N-Cbz-3-aminopiperidine(711002-74-3)
• EPA Substance Registry System: 1-N-Cbz-3-aminopiperidine(711002-74-3)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26-36
• RIDADR: UN1760
• Hazardous Substances Data: 711002-74-3(Hazardous Substances Data)

Usage

Chemical Properties

Yellow oil

InChI:InChI=1/C13H18N2O2/c14-12-7-4-8-15(9-12)13(16)17-10-11-5-2-1-3-6-11/h1-3,5-6,12H,4,7-10,14H2

Upstream product

• 68471-58-9 1-(benzyloxycarbonyl)-1,2,3,4-tetrahydropyridine 
• 3742-91-4 N-(benzyloxycarbonyl)piperidine 
• 406213-47-6 3-t-butoxycarbonylaminopiperidin-1-carboxylic acid benzyl ester 

Downstream Products

• 1041399-57-8 benzyl 3-ureidopiperidine-1-carboxylate 
• 850246-61-6 benzyl 3-[(cyanomethyl)amino]piperidine-1-carboxylate 

Relevant articles and documents

β-Functionalization of Saturated Aza-Heterocycles Enabled by Organic Photoredox Catalysis

The direct β-functionalization of saturated aza-heterocycles has remained a synthetic challenge because of the remote and unactivated nature of β-C-H bonds in these motifs. Herein, we demonstrate the β-functionalization of saturated aza-heterocycles enabl

HETEROCYCLIC TYROSINE KINASE INHIBITORS

The present invention provides compounds useful as inhibitors of Tec family kinases, compositions thereof, and methods of using the same. In certain embodiments, the present invention provides pharmaceutical formulations comprising provided compounds. In certain embodiments, the present invention provides a method of decreasing enzymatic activity of a Tec kinase family member. In some embodiments, such methods include contacting a Tec kinase family member with an effective amount of a Tec kinase family member inhibitor. In certain embodiments, the present invention provides a method of treating a disorder responsive to Tec kinase family inhibition in a subject in need thereof.