711029-84-4Relevant academic research and scientific papers
CCR5 antagonists as anti-HIV-1 agents. Part 2: Synthesis and biological evaluation of N-[3-(4-benzylpiperidin-1-yl)propyl]-N,N′- diphenylureas
Imamura, Shinichi,Kurasawa, Osamu,Nara, Yoshi,Ichikawa, Takashi,Nishikawa, Youichi,Iida, Takehiro,Hashiguchi, Shohei,Kanzaki, Naoyuki,Iizawa, Yuji,Baba, Masanori,Sugihara, Yoshihiro
, p. 2295 - 2306 (2007/10/03)
We have previously reported the novel lead compound 1a as a CCR5 antagonist for treatment of HIV-1 infection. SAR studies on incorporating various acyl groups as a replacement for the 5-oxopyrrolidine-3-carbonyl group of the lead structure resulted in the
