71153-74-7

Basic information

• Product Name: 3,4-dihydro-6-methyl-2H-1-benzothiopyran
• Synonyms: 3,4-dihydro-6-methyl-2H-1-benzothiopyran
• CAS NO: 71153-74-7
• Molecular Formula: C₁₀H₁₂S
• Molecular Weight: 164.26728
• EINECS: 275-221-0
• Mol File: 71153-74-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 264.1°C at 760 mmHg
• Flash Point: 109.2°C
• Appearance: /
• Density: 1.08g/cm³
• Vapor Pressure: 0.0162mmHg at 25°C
• Refractive Index: 1.591
• CAS DataBase Reference: 3,4-dihydro-6-methyl-2H-1-benzothiopyran(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-dihydro-6-methyl-2H-1-benzothiopyran(71153-74-7)
• EPA Substance Registry System: 3,4-dihydro-6-methyl-2H-1-benzothiopyran(71153-74-7)

Safety Data

• Hazardous Substances Data: 71153-74-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H12S/c1-8-4-5-10-9(7-8)3-2-6-11-10/h4-5,7H,2-3,6H2,1H3

Upstream product

• 106-45-6 para-thiocresol 
• 504-63-2 trimethyleneglycol 
• 13739-35-0 3-[(4-methylphenyl)thio]propionic acid 
• 3147-30-6 γ-chloropropyl 4-methylphenyl sulphide 

Downstream Products

• 1421435-04-2 2-[2-(6-methylthiochroman-4-ylidene)hydrazinyl]-5-phenylthiazole 
• 1077-61-8 6-methylthiochroman-S,S-dioxide 

Relevant articles and documents

Direct Access to S-Heterocycles by Scandium(III) Triflate Catalyzed Cyclization of Aromatic Thiols and Diols

A simple and environmentally friendly method to prepare S-heterocycles by cyclization of aromatic thiols and diols with H2O as a byproduct is described. The Sc(OTf)3-catalyzed dehydrative cyclizations of aromatic thiols and diols provided the corresponding thiopyran and thiophene derivatives. Control experiments were also performed to obtain insights into the reaction pathway.

MODERN FRIEDEL-CRAFTS CHEMISTRY. XI. CYCLIZATION OF ARYL HALOALKYL SULFONES, ARYLSULFONYLACYL CHLORIDES AND THEIR CORRESPONDING SULFIDES

The sulfone group deactivation for cyclialkylation and cycliacylation reactions in the presence of Friedel-Crafts catalysts was demonstrated in a number of aryl chloroalkylsulfones (1-8) and arylsulfonylacyl chlorides (17a-22a), respectively.As expected, the corresponding arylchloroalkyl sulfides (9-16) and arylmercaptoacyl chlorides (13a-28a) underwent ring-closure reaction in most cases under the same conditions.The ease of cyclization was governed by the ring size, the stability of the attacking carbocation and the nucleophilicity of the aryl moiety.Also, the behaviour of benzyl sulfones (29, 31a, and 32a) and sulfides (33, 34a and 36a) was inconsistent.Noteworthy, the Friedel-Crafts cyclization reaction is thus considered an accessible method for the synthesis of compounds 37-41 and 45, 51.