3147-30-6Relevant academic research and scientific papers
Nickel-Catalyzed Reductive Thiolation of Unactivated Alkyl Bromides and Arenesulfonyl Cyanides
Rao, Weidong,Wang, Fei,Wang, Shun-Yi
, p. 8970 - 8979 (2021/07/19)
The cross-electrophile coupling between unactivated alkyl bromides with arenesulfonyl cyanides catalyzed by Ni(acac)2under reductive conditions to form unsymmetrical sulfides is developed. This approach for sulfide synthesis is practical, relies on available, unfunctionalized materials such as alkyl (pseudo)halides, and is scalable. This catalytic strategy provides a complementary method for the preparation of unsymmetrical alkyl-aryl sulfides under mild conditions with good functional group tolerance.
Increasing Complexity: A Practical Synthetic Approach to Three-Dimensional, Cyclic Sulfoximines and First Insights into Their in Vitro Properties
Boulard, Emilie,Ganzer, Ursula,Lücking, Ulrich,Lienau, Philip,Oertel, Luisa,Sch?fer, Martina,Zibulski, Vivien
, (2020/03/23)
A short synthetic approach with broad scope to access five- to seven-membered cyclic sulfoximines in only two to three steps from readily available thiophenols is reported. Thus, simple building blocks were converted to complex molecular structures by a s
Synthesis and QSAR studies on hypotensive 1-[3-(4-substituted phenylthio) propyl]-4-(substituted phenyl) piperazines
Saxena, Anil K.,Rao, Jyoti,Chakrabarty, Ruchika,Saxena, Mridula,Srimal
, p. 1708 - 1712 (2007/10/03)
A series of 1-[3-(4-substituted phenylthio) propyl]-4-(substituted phenyl) piperazines has been synthesized and evaluated for hypotensive activity. The QSAR studies indicate that resonance and hydrophobic parameters of the aryl substituents are important
Synthesis of N-heterocyclics as Potential CNS/CVS Agents
Rao, Jyoti,Saxena, Anil K.,Saxena, R. M.,Singh, H. K.,Kar, K.,Srimal, R. C.
, p. 761 - 765 (2007/10/02)
A number of N-heterocyclics (6-13, 19-21) have been synthesized by the condensation of γ-chloropropylaryl sulphides and sulphones (3-5 and 18) with appropriate nitrogen heterocyclics.The 4-aminophenyl derivatives in case of su
