7116-51-0

Basic information

• Product Name: Benzene, 1-(methoxymethyl)-3-methyl-
• CAS NO: 7116-51-0
• Molecular Formula: C9H12O
• Molecular Weight: 136.194
• Mol File: 7116-51-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(methoxymethyl)-3-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(methoxymethyl)-3-methyl-(7116-51-0)
• EPA Substance Registry System: Benzene, 1-(methoxymethyl)-3-methyl-(7116-51-0)

Safety Data

• Hazardous Substances Data: 7116-51-0(Hazardous Substances Data)

Upstream product

• 17369-57-2 3-methylbenzyl acetate 
• 587-03-1 3-methylbenzyl alcohol 
• 74-96-4 ethyl bromide 
• 60-29-7 diethyl ether 
• 119858-82-1 m-chloromethyl(methoxymethyl)benzene 
• 620-19-9 1-chloromethyl-3-methyl-benzene 
• 91963-24-5 methyl 4-methylindanone-2-carboxylate 
• 67-56-1 methanol 
• 74-88-4 methyl iodide 
• 83674-23-1 3-Methylbenzyl pivalate 
• 108-38-3 m-xylene 
• 591-17-3 meta-bromotoluene 
• 27490-32-0 tributyl(methoxymethyl)stannane 
• 620-13-3 1-bromomethyl-3-methyl-benzene 

Downstream Products

• 55329-66-3 N-(m-methylbenzyl)acetamide 
• 125553-01-7 N-(3-methylbenzyl)benzamide 
• 620-22-4 3-Methylbenzonitrile 
• 620-23-5 m-tolyl aldehyde 

Relevant articles and documents

HYDANTOIN DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY DISORDERS

This invention relates to compounds of the Formula: (I); or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF-α or combinations thereof.

The Photochemistry of Methoxy-Substituted Benzyl Acetates and Benzyl Pivalates: Homolytic vs Heterolytic Cleavage

The multiple methoxy-substituted benzyl acetates (3g-i) and benzyl pivalates (4g-i) have been photolyzed in methanol solution.The products of these reactions are derived from two critical intermediates; the benzyl radical/acyloxy radical pair and the benzyl cation/carboxylate anion pair.As predicted by the meta effect, the yield of ion-derived product, the methyl ether in this case, was enhanced by the presence of the m-methoxy groups.The yield of ether, for the acetate esters, varied from 2percent for the 4-methoxy-substituted ester to 66percent for the 3,4,5-trimethoxy-substituted ester.In contrast, the yield of ether, for the pivalate esters, varied from 1percent for the 4-methoxy-substituted ester to 20percent for the 3,4,5-trimethoxy-substituted one.The meta effect does not explain these differences; electron transfer converting the radical pair to the ion pair is still an important pathway in the mechanism for ion formation.A quantitative analysis of the yield of the ethers was done in order to obtain the electron-transfer rate constants.This analysis revealed that the yield of the ethers was higher than expected based on previous results for other substituted benzyl acetates.A possible explanation for this discrepancy is that internal return of the radical pair to starting material for the acetate esters is more efficient than for the pivalate esters.Also, the esters 3k and 3l, were prepared to study the effect of electron-withdrawing groups in the meta position.For these esters, the benzylic cleavage reactions were inefficient and an isomerization reaction, the benzvalene rearrangement, was competitive.

Anodic Oxidation of Xylenes. Electrochemical Obtention of Cyclohexa-1,4-diene Derivatives

cis- and trans-3,6-dimethoxy-3,6-dimethylcyclohexa-1,4-dienes obtained by methoxylation of p-xylene were completely separated.The unequivocal structure of the trans isomer was assigned by X-ray diffraction, and the cis:trans ratio is satisfactorily explained by an EECrCp mechanism.When the substrates were p- and o-xylene, the nuclear-addition products were obtained in a two-electron process, but when the substrate was m-xylene, the major muclear-addition product was obtained in a four-electron process.