71173-10-9Relevant academic research and scientific papers
NOVEL PYRIDAZONES AND TRIAZINONES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION
-
Page/Page column 83, (2016/02/29)
The invention provides novel compounds having the general formula wherein R1, R2, R3, X and a are as described in the description and in the claims, as well as or pharmaceutically acceptable salts thereof. The invention also contains compositions including the compounds and methods of using the compounds.
Structure-activity relationships in a series of 8-substituted xanthines as A1-adenosine receptor antagonists
Strappaghetti, Giovannella,Corsano, Stefano,Barbaro, Roberta,Giannaccini, Gino,Betti, Laura
, p. 575 - 583 (2007/10/03)
A series of 8-substituted xanthines were synthesized and their affinity in vitro towards A1, A2A-adenosine receptors was evaluated by radioligand receptor binding assays. All compounds showed a greater affinity and selectivity toward
