7118-55-0

Basic information

• Product Name: 4-methyl-N-phenyl-benzenecarboximidamide
• CAS NO: 7118-55-0
• Molecular Formula: C₁₄H₁₄N₂
• Molecular Weight: 210.279
• Mol File: 7118-55-0.mol
• Article Data: 21

Chemical Properties

• CAS DataBase Reference: 4-methyl-N-phenyl-benzenecarboximidamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-N-phenyl-benzenecarboximidamide(7118-55-0)
• EPA Substance Registry System: 4-methyl-N-phenyl-benzenecarboximidamide(7118-55-0)

Safety Data

• Hazardous Substances Data: 7118-55-0(Hazardous Substances Data)

Upstream product

• 4484-20-2 aniline benzenesulfonate 
• 104-85-8 para-methylbenzonitrile 
• 62-53-3 aniline 
• 619-55-6 para-methylbenzamide 

Downstream Products

• 67595-33-9 3-phenyl-4-p-tolyl-2,2,6,6-tetrakis-trifluoromethyl-3,6-dihydro-2H-[1,3,5]oxadiazine 
• 1423125-89-6 1,4-diphenyl-2-(p-tolyl)-1H-imidazole 
• 16112-44-0 2-(4-methylphenyl)-4-phenyl-quinazoline 
• 1453261-06-7 C₇₄H₁₂N₂ 
• 1445952-35-1 phenyl(2-(p-tolyl)-1H-indol-3-yl)methanone 
• 94863-18-0 1,3-diphenyl-5-(p-tolyl)-1H-1,2,4-triazole 
• 2620-80-6 2-(4-methylphenyl)-1-phenyl-1H-benzo[d]imidazole 

Relevant articles and documents

Photoredox synthesis of functionalized quinazolinesviacopper-catalyzed aerobic oxidative Csp2-H annulation of amidines with terminal alkynes

We have developed a visible light-induced photo-redox copper-catalyzed oxidative Csp2-H annulation (Friedel-Crafts-type cyclization) of amidines with terminal alkynes at room temperature to synthesize functionalized quinazolines. We report copp

Transition-Metal-Free Synthesis of 1,2-diphenyl-1H-benzo[d] Imidazole Derivatives from N-phenylbenzimidamides and Cyclohexanones

A transition-metal-free strategy for the formation of 1,2-diphenyl-1H-benzo[d] imidazoles from N-phenylbenzimidamides and cyclohexanones is introduced. This is the first report on the direct synthesis of 1,2-diphenyl-1H-benzo[d] imidazoles from cyclohexanones and N-phenylbenzimidamides via iodine- promoted oxidative cyclization. Non-aromatic cyclohexanones were smoothly dehydrogenated, and acted as an aryl source using oxygen as a green oxidant. The catalytic use of iodine makes this method quite simple, more economical and convenient. Under optimized conditions, various substituted 1,2-diphenyl-1H-benzo[d] imidazoles were smoothly reacted, and the desired substituted imidazoles were generated with moderate to excellent yields. (Figure presented.).

Base-Mediated Amination of Alcohols Using Amidines

Novel and efficient base-mediated N-alkylation and amidation of amidines with alcohols have been developed, which can be carried out in one-pot reaction conditions, which allows for the synthesis of a wide range of N-alkyl amines and free amides in good to excellent yields with high atom economy. In contrast to borrowing hydrogen/hydrogen autotransfer or oxidative-type N-alkylation reactions, in which alcohols are activated by transition-metal-catalyzed or oxidative aerobic dehydrogenation, the use of amidines provides an effective surrogate of amines. This circumvents the inherent necessity in N-alkylation of an oxidant or a catalyst to be stabilized by ligands.