712-76-5 Usage
Uses
Used in Pharmaceutical Synthesis:
4-Phenylbenzylamine is used as a key intermediate for the synthesis of various pharmaceutical compounds, including:
1. Squaric acid asymmetric diamides of glycopeptide antibiotics: These compounds are known for their potent antimicrobial properties and are used to treat a range of bacterial infections.
2. Asymmetric diamides of daunomycin and carminomycin: These are anthracycline antibiotics with significant antineoplastic activity, used in the treatment of various types of cancer.
3. N-(biphenyl-4-ylmethyl)-1-hydroxy-6-thioxo-1,6-dihydropyridine-2-carboxamide: 4-PHENYLBENZYLAMINE has potential applications in the development of new drugs targeting specific diseases.
Used in Medical Imaging:
4-Phenylbenzylamine is also used in the synthesis of Gd3+ chelates of DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetate) type ligands. These chelates are essential components in the field of medical imaging, particularly in magnetic resonance imaging (MRI), where they enhance the contrast and improve the visualization of specific tissues and organs.
Check Digit Verification of cas no
The CAS Registry Mumber 712-76-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,1 and 2 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 712-76:
(5*7)+(4*1)+(3*2)+(2*7)+(1*6)=65
65 % 10 = 5
So 712-76-5 is a valid CAS Registry Number.
InChI:InChI=1/C13H13N/c14-10-11-6-8-13(9-7-11)12-4-2-1-3-5-12/h1-9H,10,14H2/p+1
712-76-5Relevant academic research and scientific papers
Cobalt pincer complexes for catalytic reduction of nitriles to primary amines
Schneek?nig, Jacob,Tannert, Bianca,Hornke, Helen,Beller, Matthias,Junge, Kathrin
, p. 1779 - 1783 (2019/04/27)
Various cobalt pincer type complexes 1-6 were applied for the catalytic hydrogenation of nitriles to amines. Among these, catalyst 4 is the most efficient, allowing the reduction of aromatic as well as aliphatic nitriles in moderate to excellent yields.
Organic reaction in water. Part 3: A facile method for reduction of aromatic rings using a Raney Ni-Al alloy in dilute aqueous alkaline solution under mild conditions
Tsukinoki, Takehito,Kanda, Tadashige,Liu, Guo-Bin,Tsuzuki, Hirohisa,Tashiro, Masashi
, p. 5865 - 5868 (2007/10/03)
Reduction of aromatic rings such as phenol, naphthalenes, biphenyls, acenaphthene, and acenaphthylene was smoothly performed using a Raney Ni-Al alloy in dilute aqueous alkaline solution without any organic solvents at 90°C under atmospheric pressure, and the corresponding reduced compounds were obtained in high yields. (C) 2000 Elsevier Science Ltd.
