71208-55-4 Usage
Uses
Diethyl 2-Methylpropanedioate Carprofen is an intermediate in the synthesis of Carprofen (C184350), a non steroidal anti-inflammatory that is used by veterinarians for the relief of arthritic systems in dogs. It can be used for joint pain or post operative inflammation. Carprofen, is also used for the relief from pain and inflammation associated with osteoarthritis, hip dysplasia and other joint issues.
Check Digit Verification of cas no
The CAS Registry Mumber 71208-55-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,2,0 and 8 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 71208-55:
(7*7)+(6*1)+(5*2)+(4*0)+(3*8)+(2*5)+(1*5)=104
104 % 10 = 4
So 71208-55-4 is a valid CAS Registry Number.
InChI:InChI=1/C20H20ClNO4/c1-3-25-19(23)16(20(24)26-4-2)9-12-5-7-14-15-11-13(21)6-8-17(15)22-18(14)10-12/h5-8,10-11,16,22H,3-4,9H2,1-2H3
71208-55-4Relevant articles and documents
Isolation and identification of an unusual impurity in an intermediate of Rimadyl (carprofen)
Tucker, John L.,DeVries, Keith M.,Hammen, Philip D.,Rose, Peter R.,Raymer, Brian K.,Rescek, Diane
, p. 1681 - 1688 (2007/10/03)
The isolation and identification of an unknown process related impurity in a key intermediate of Rimadyl (carprofen) is described. The structure of the unknown was evaluated by NMR spectral analysis and eventually confirmed by single crystal X-Ray. A re-slurry in warm acetic acid was found to reduce the level of the unknown to an acceptable level.
Process of making 6-chloro-α-methyl-carbazole-2-acetic acid
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, (2008/06/13)
The aromatization of (6-chloro-1,2,3,4-tetrahydro-2-carbazolyl)-methyl-malonic acid dialkyl ester, utilizing chlorine and subsequent conversion of the resulting product to 6-chloro-α-methyl-carbazole-2-acetic acid by hydrolysis and decarboxylation are described.
