Welcome to LookChem.com Sign In|Join Free
  • or
18-Hydroxy-4-androstene-3,17-dione is a naturally occurring steroid hormone derivative, which is a metabolite of the hormone aldosterone. It is structurally similar to other androgens and is involved in various physiological processes, including the regulation of electrolyte balance and blood pressure. 18-hydroxy-4-androstene-3,17-dione is synthesized in the adrenal glands and plays a role in the renin-angiotensin-aldosterone system, which is crucial for maintaining fluid and electrolyte homeostasis in the body. The presence of 18-hydroxy-4-androstene-3,17-dione can be an indicator of certain adrenal disorders, and its levels are often monitored in medical diagnostics.

7121-60-0

Post Buying Request

7121-60-0 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

7121-60-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 7121-60-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,1,2 and 1 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 7121-60:
(6*7)+(5*1)+(4*2)+(3*1)+(2*6)+(1*0)=70
70 % 10 = 0
So 7121-60-0 is a valid CAS Registry Number.
InChI:InChI=1/C19H26O3/c1-18-8-6-13(21)10-12(18)2-3-14-15(18)7-9-19(11-20)16(14)4-5-17(19)22/h10,14-16,20H,2-9,11H2,1H3/t14-,15+,16+,18+,19-/m1/s1

7121-60-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (8R,9S,10R,13S,14S)-13-(hydroxymethyl)-10-methyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione

1.2 Other means of identification

Product number -
Other names Androst-4-ene-3,17-dione,18-hydroxy

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7121-60-0 SDS

7121-60-0Downstream Products

7121-60-0Relevant academic research and scientific papers

An improved synthesis of 18-norandrost-4-ene-3,17-dione

Davioud,Schambel,Viger,Marquet

, p. 141 - 144 (1993)

We describe the synthesis of 13β- and 13α-H-18-nor-androst-4-ene-3,17- dione (1a and 1b) from 18-hydroxyprogesterone (18 → 20) hemiketal, via the 18-acetoxy-17β-hydroxyandrost-4-en-3-one formed by a modified Baeyer- Villiger reaction. Saponification of 18-acetoxyandrost-4-ene-3,17-dione with sonication, then retroaldolization in the presence of a formaldehyde trap, methone, afforded the mixture of 1a and 1b with 80% yield in a 'one-pot' procedure and at room temperature. This yield was greatly improved, compared with the already published procedure.

SYNTHESIS OF 18-SUBSTITUTED ANDROST-4-EN-3-ONE DERIVATIVES AS POTENTIAL INHIBITORS OF ALDOSTERONE BIOSYNTHESIS

Viger, Antoinette,Coustal, Suzy,Schambel, Philippe,Marquet, Andree

, p. 7309 - 7322 (2007/10/02)

Androst-4-en-3-one derivatives substituted at the 18-methyl group bearing a 17-keto or 17-spirolactone function have been synthesized and tested in vitro as inhibitors of aldosterone biosynthesis

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 7121-60-0