712351-27-4Relevant articles and documents
Solid-phase intramolecular N-acyliminium Pictet-Spengler reactions as crossroads to scaffold diversity
Nielsen, Thomas E.,Meldal, Morten
, p. 3765 - 3773 (2007/10/03)
A novel solid-phase intramolecular Pictet-Spengler reaction is presented. The approach utilizes masked aldehyde building blocks protected as their N-Boc-1,3-oxazinanes for the clean generation of solid-supported aldehydes. When exposed to simple acidic tr