712352-08-4

Basic information

• Product Name: (+)-N,N-BIS[(1R)-1-PHENYLETHYL]-DINAPHTHO[2,1-D:1',2'-F][1,3,2]DIOXAPHOSPHEPIN-4-AMINE, (11BR)
• Synonyms: (+)-N,N-BIS[(1R)-1-PHENYLETHYL]-DINAPHTHO[2,1-D:1',2'-F][1,3,2]DIOXAPHOSPHEPIN-4-AMINE, (11BR);(S,R,R)-(+)-(3,5-DIOXA-4-PHOSPHA-CYCLOHEPTA[2,1-A:3,4-A']DINAPHTHALEN-4-YL)BIS(1-PHENYLETHYL)AMINE;N,N-Bis((R)-1-phenylethyl)dinaphtho-[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine
• CAS NO: 712352-08-4
• Molecular Formula: C36H30NO2P
• Molecular Weight: 539.602661
• Mol File: 712352-08-4.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 710.7±63.0 °C(Predicted)
• Appearance: /
• PKA: -0.57±0.20(Predicted)
• CAS DataBase Reference: (+)-N,N-BIS[(1R)-1-PHENYLETHYL]-DINAPHTHO[2,1-D:1',2'-F][1,3,2]DIOXAPHOSPHEPIN-4-AMINE, (11BR)(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-N,N-BIS[(1R)-1-PHENYLETHYL]-DINAPHTHO[2,1-D:1',2'-F][1,3,2]DIOXAPHOSPHEPIN-4-AMINE, (11BR)(712352-08-4)
• EPA Substance Registry System: (+)-N,N-BIS[(1R)-1-PHENYLETHYL]-DINAPHTHO[2,1-D:1',2'-F][1,3,2]DIOXAPHOSPHEPIN-4-AMINE, (11BR)(712352-08-4)

Safety Data

• Hazardous Substances Data: 712352-08-4(Hazardous Substances Data)

Usage

General Description

"(+)-N,N-BIS[(1R)-1-PHENYLETHYL]-DINAPHTHO[2,1-D:1',2'-F][1,3,2]DIOXAPHOSPHEPIN-4-AMINE, (11BR) is a chemical compound with a complex molecular structure. It contains two phosphorous atoms and is a chiral molecule with a specific stereochemistry. The compound is often used as a ligand in asymmetric catalysis and can be involved in the formation of complex organic molecules. Its unique structure and properties make it a valuable tool in organic synthesis and chemical research."

Upstream product

• 21003-56-5 (1S,1'S)-bis(1-phenylethyl)amine 
• 10024-74-5 (R,R)-N,N-bis-(1-phenylethyl)amine 
• 602-09-5 1,1'-bi-2-naphthol 
• 18531-94-7 (R)-1,1'-Bi-2-naphthol 
• 18531-99-2 (S)-[1,1']-binaphthalenyl-2,2'-diol 
• 137156-22-0 binaphthol chlorophosphite 
• 777067-25-1 [(S,S)-bis(α-methylbenzyl)amino]phosphorous dichloride 
• 98-86-2 acetophenone 
• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 40648-92-8 hydrochloride salt of (1S,1'S)-bis(1-phenylethyl)amine 

Relevant articles and documents

Enantioselective Allylation of Alkenyl Boronates Promotes a 1,2-Metalate Rearrangement with 1,3-Diastereocontrol

Alkenyl boronates add to Ir(π-allyl) intermediates with high enantioselectivity. A 1,2-metalate shift forms a second C-C bond and sets a 1,3-stereochemical relationship. The three-component coupling provides tertiary boronic esters that can undergo multiple additional functionalizations. An extension to trisubstituted olefins sets three contiguous stereocenters.

Development of Axially Chiral Cyclo-Biaryldiol Ligands with Adjustable Dihedral Angles

A new type of axially chiral cyclo-[1,1′-biphenyl]-2,2′-diol (CYCNOL) ligands with adjustable dihedral angles have been developed by varying the bridge chain length. Eight-, nine- and ten-membered cyclo-ligands were prepared and evaluated by using two representative examples: enantioselective additions of diethylzinc to aldehydes and organometallic reagents to enones. The results revealed that the fine regulation of dihedral angles through variation of the bridge chain length was effective in the asymmetric synthesis.

Efficient, selective, and green: Catalyst tuning for highly enatioselective reactions of ethylene

Fine tuning of the biaryl and amino moieties of Feringa's phosphoramidite ligands yields structurally simpler, yet more efficient and selective, ligands for asymmetric hydrovinylation of vinylarenes and acylic 1,3-dienes. The enantioselectivities and yields observed in the formation of the 3-arylbutenes are among the highest for all asymmetric catalytic processes reported to date for the synthesis of intermediates for the widely used antiinflammatory 2-arylpropionic acids including naproxen, ibuprofen, fenoprofen, and flurbiprofen.