71236-54-9Relevant academic research and scientific papers
Reductive Coupling of Carbonyl Compounds with Zinc and Trimethylchlorosilane To Produce O-Silylated Pinacols. Effect of Ultrasonic Waves
So, Jeung-Ho,Park, Moon-Kyeu,Boudjouk, Philip
, p. 5871 - 5875 (2007/10/02)
Trimethylchlorosilane reacts with carbonyl compounds in the presence of zinc to give O-silylated pinacols, vicinal bis(trimethylsiloxy)alkanes, in good yields via reductive dimerization.This is very mild route to bis(siloxy)alkanes, which are easily converted to pinacols or pinacolones in excellent yields.Electron-donating groups accelerate coupling while electron-withdrawing groups have an inhibiting effect.Cross-coupling reactions yield a mixture of bis(siloxy)alkanes.Ultrasonic irradiations of these reactions increases the yields up to 50percent compared to stirring at the same temperature.
