71239-85-5

Basic information

• Product Name: Boc-3-(2-pyridyl)-L-alanine
• Synonyms: BOC-(S)-2-AMINO-3-(2'-PYRIDYL)PROPANOIC ACID;BOC-BETA-(2-PYRIDYL)-ALA-OH;BOC-BETA-(2-PYRIDYL)-L-ALANINE;BOC-ALA-BETA-(2-PYRIDYL)-OH;BOC-ALA(2'-PYRIDYL)-OH;BOC-ALA(2-PYRIDYL)-OH;BOC-ALA(2-PYRI)-OH;BOC-L-2-PYRIDYLALA
• CAS NO: 71239-85-5
• Molecular Formula: C₁₃H₁₈N₂O₄
• Molecular Weight: 266.29
• Product Categories: Amino Acids;Phenylalanine analogs and other aromatic alpha amino acids;a-amino
• Mol File: 71239-85-5.mol
• Article Data: 1

Chemical Properties

• Melting Point: 141 °C(dec.)
• Boiling Point: 409.5°C (rough estimate)
• Flash Point: 218 °C
• Appearance: /Solid
• Density: 1.1738 (rough estimate)
• Vapor Pressure: 2.09E-08mmHg at 25°C
• Refractive Index: 1.6450 (estimate)
• Storage Temp.: Store at 0-5°C
• Solubility: slightly sol. in Methanol
• PKA: 3.09±0.10(Predicted)
• BRN: 6416850
• CAS DataBase Reference: Boc-3-(2-pyridyl)-L-alanine(CAS DataBase Reference)
• NIST Chemistry Reference: Boc-3-(2-pyridyl)-L-alanine(71239-85-5)
• EPA Substance Registry System: Boc-3-(2-pyridyl)-L-alanine(71239-85-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-60-37
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 71239-85-5(Hazardous Substances Data)

Usage

Chemical Properties

Off-white to beige powder

InChI:InChI=1/C13H18N2O4/c1-13(2,3)19-12(18)15-10(11(16)17)8-9-6-4-5-7-14-9/h4-7,10H,8H2,1-3H3,(H,15,18)(H,16,17)/t10-/m1/s1

Upstream product

• 185379-37-7 N^α-acetyl-β-(2-pyridyl)-DL-alanine ethyl ester 
• 19814-60-9 diethyl 2-acetamido-2-(methylpyridin-2-yl)malonate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 37535-51-6 (S)-2-amino-3-(pyridin-2-yl)propanoic acid 
• 74164-26-4 N^α-acetyl-β-(2-pyridyl)-L-alanine 

Downstream Products

• 553668-09-0 5-[(S)-2-((S)-2-tert-Butoxycarbonylamino-3-pyridin-2-yl-propionylamino)-2-pentylcarbamoyl-ethyl]-2-methoxycarbonylmethoxy-benzoic acid methyl ester 
• 337530-28-6 benzyl [[(2S)-2-[(tert-butoxycarbonyl)amino]-3-(pyridin-2-yl)propanoyl]amino]acetate 
• 337530-24-2 (2S)-2-(tert-butoxycarbonylamino)-N-[2-[4-(4-chlorophenyl)-1-piperazinyl]-2-oxoethyl]-3-(2-pyridyl)propanamide 
• 713138-62-6 (S)-N'-tert.-butoxycarbonyl-N-(2-amino-4-chloro)phenyl-3-(pyridin-2-yl)-alaninamide 
• 713138-61-5 (S)-N'-tert.-butoxycarbonyl-N-(2-amino-5-chloro)phenyl-3-(pyridin-2-yl)-alaninamide 
• 348619-79-4 2-Amino-3-(pyridin-2-yl)-1-propanol 
• 37535-51-6 (S)-2-amino-3-(pyridin-2-yl)propanoic acid 
• 1416468-46-6 (4aS,8aR)-2-{1-[(2S)-2-amino-3-(pyridin-2-yl)propanoyl]piperidin-4-yl}-4-(3,4-dimethoxyphenyl)-4a,5,6,7,8,8a-hexahydrophthalazin-1(2H)-one hydrochloride 
• 1416468-93-3 tert-butyl [(2S)-1-{4-[(4aS,8aR)-4-(3,4-dimethoxyphenyl)-1-oxo-4a,5,6,7,8,8a-hexahydrophthalazin-2(1H)-yl]piperidin-1-yl}-1-oxo-3-(pyridin-2-yl)propan-2-yl]carbamate 
• 1416467-43-0 4-[5-(cyclopropylmethoxy)-1,3-benzodioxol-4-yl]-N-[(2S)-1-{4-[(4aS,8aR)-4-(3,4-dimethoxyphenyl)-1-oxo-4a,5,6,7,8,8a-hexahydrophthalazin-2(1H)-yl]piperidin-1-yl}-1-oxo-3-(pyridin-2-yl)propan-2-yl]-5H-pyrrolo[3,2-d]pyrimidine-7-carboxamide 
• 1416467-42-9 4-[5-(cyclopropylmethoxy)-1,3-benzodioxol-4-yl]-N-[(2S)-1-{4-[(4aS,8aR)-4-(3,4-dimethoxyphenyl)-1-oxo-4a,5,6,7,8,8a-hexahydrophthalazin-2(1H)-yl]piperidin-1-yl}-1-oxo-3-(pyridin-2-yl)propan-2-yl]-6-methyl-5H-pyrrolo[3,2-d]pyrimidine-7-carboxamide 
• 935887-93-7 C₂₉H₃₃N₃O₅ 

Relevant articles and documents

Studies on polypeptides XXXII. Solid-phase synthesis of RNase S-peptide 1-14 analogues; replacement of histidine-12 by β-(2-pyridyl)-L-alanine and β-(4-pyridyl)-L-alanine

The synthesis of two analogues of the N-terminal tetradecapeptide of ribonuclease A (RNase S-peptide 1-14), in which the active site histidine-12 residue is replaced by β-(2-pyridyl)-L-alanine and β-(4-pyridyl)-L-alanine, has been accomplished by the solid-phase method.The enantiomers of β-(2-pyridyl)alanine were obtained by chymotryptic hydrolysis of its racemic Nα-acetyl ethyl ester.The Boc derivative of both L-amino acids has been synthesized.