71255-53-3 Usage
Description
N-(2-aminophenyl)-4-methylbenzamide is an organic compound with the molecular formula C14H14N2O. It is a derivative of benzamide, featuring an amino group attached to the phenyl ring. N-(2-aminophenyl)-4-methylbenzamide is known for its potential applications in various fields due to its unique chemical structure and properties.
Uses
Used in Pharmaceutical Industry:
N-(2-aminophenyl)-4-methylbenzamide is used as a chemical probe for chemoproteomics profiling of HDAC inhibitors. It plays a crucial role in selectively targeting HDAC (histone deacetylase) complexes, which are important enzymes involved in the regulation of gene expression. By modulating the activity of these complexes, N-(2-aminophenyl)-4-methylbenzamide can potentially contribute to the development of novel therapeutic strategies for various diseases, including cancer and neurological disorders.
Used in Research and Development:
In the field of research and development, N-(2-aminophenyl)-4-methylbenzamide serves as a valuable tool for studying the structure, function, and regulation of HDAC enzymes. Its use in chemoproteomics profiling allows scientists to gain a deeper understanding of the complex interactions between HDAC inhibitors and their target proteins, which can lead to the discovery of new drug targets and the development of more effective treatments for various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 71255-53-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,2,5 and 5 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 71255-53:
(7*7)+(6*1)+(5*2)+(4*5)+(3*5)+(2*5)+(1*3)=113
113 % 10 = 3
So 71255-53-3 is a valid CAS Registry Number.
71255-53-3Relevant articles and documents
Copper-catalyzed regioselective 2-amination of o-haloanilides with aqueous ammonia
Tang, Yan-Ling,Li, Mei-Ling,Gao, Jin-Chun,Sun, Yun,Qu, Lu,Huang, Feng,Mao, Ze-Wei
supporting information, (2021/04/02)
An efficient Cu(II)-vasicine catalytic system has been developed for intramolecular C[sbnd]N bond formation. In this way, regioselective 2-amination of o-haloanilides with aqueous ammonia in EtOH has been achieved. This strategy provides several advantages, such as good regioselectivity, high yields and functional group tolerance.
Facile synthesis of thiazoles via an intramolecular thia-Michael strategy
Sasmal, Pradip K.,Sridhar,Iqbal, Javed
, p. 8661 - 8665 (2007/10/03)
A mild and efficient method for the synthesis of substituted thiazoles is reported via one-pot N-desilylation, thioacylation/oxythioacylation/thiothioacylation followed by thia-Michael cycloisomerisation. This method has a general applicability to introdu
