7127-73-3 Usage
Uses
Used in Pharmaceutical Development:
2,3,6,7-Tetrademethoxytylophorin is used as a lead compound in pharmaceutical research for its anti-inflammatory properties, which can help in the treatment of various inflammatory conditions. Its ability to reduce inflammation without causing significant side effects makes it a valuable asset in drug development.
Used in Anticancer Applications:
In the field of oncology, 2,3,6,7-Tetrademethoxytylophorin is used as a potential anticancer agent. Its mechanism of action involves targeting various cellular pathways and processes that contribute to tumor growth and progression, making it a promising candidate for the development of novel cancer therapies.
Used in Immunomodulation:
2,3,6,7-Tetrademethoxytylophorin is used as an immunomodulatory agent to regulate the immune system. Its potential to modulate immune responses can be beneficial in the treatment of autoimmune diseases and conditions where the immune system is either overactive or underactive.
Used in Autophagy Modulation:
In the biotechnology industry, 2,3,6,7-Tetrademethoxytylophorin is used as a modulator of autophagy, a cellular process that plays a crucial role in maintaining cellular homeostasis and preventing diseases. Its ability to influence autophagy makes it a valuable tool in the development of therapies targeting neurodegenerative diseases, cancer, and other conditions associated with impaired autophagy.
Used in Drug Delivery Systems:
To enhance the bioavailability and therapeutic efficacy of 2,3,6,7-Tetrademethoxytylophorin, it is used in conjunction with various drug delivery systems. These systems, which may include organic and metallic nanoparticles, aim to improve the compound's delivery to target tissues, increasing its potential for successful treatment outcomes.
Check Digit Verification of cas no
The CAS Registry Mumber 7127-73-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,1,2 and 7 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 7127-73:
(6*7)+(5*1)+(4*2)+(3*7)+(2*7)+(1*3)=93
93 % 10 = 3
So 7127-73-3 is a valid CAS Registry Number.
7127-73-3Relevant articles and documents
Expedient synthesis and structure-activity relationships of phenanthroindolizidine and phenanthroquinolizidine alkaloids
Chuang, Ta-Hsien,Lee, Shiow-Ju,Yang, Cheng-Wei,Wu, Pei-Lin
, p. 860 - 867 (2006)
The total synthesis of alkaloids phenanthroindolizidine 1a, tylophorine 1b, and phenanthroquinolizidine 1c, has been achieved in 46%, 49%, and 42% overall yield, respectively, starting from the corresponding phenanthrene-9- carboxaldehyde. Compound 1c exhibited potent inhibition activity in three human cancer cell lines, with IC50 values ranging from 104 to 130 nM. The structure-activity relations of these alkaloids and some of their synthetic intermediates against the three cell lines were also described. The Royal Society of Chemistry 2006.
A concise palladium-catalyzed carboamination route to (±)- tylophorine
Rossiter, Lana M.,Slater, Meagan L.,Giessert, Rachel E.,Sakwa, Samuel A.,Herr, R. Jason
supporting information; experimental part, p. 9554 - 9557 (2010/03/03)
(Chemical Equation Presented) Atotal synthesis of the racemic natural product tylophorine [(±)-1] has been demonstrated using the palladium-catalyzed carboamination method developed byWolfe and co-workers. In this case, an electron-rich aryl bromide 18 wa
