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Usage

Uses

Used in Pharmaceutical Research:
5,6-Dichloroindolin-2-one is used as a research compound for its potential applications in the development of new pharmaceuticals. Its structure and properties make it a promising candidate for further investigation in drug discovery processes.
Used in Organic Synthesis:
5,6-Dichloroindolin-2-one is used as a building block in organic synthesis, allowing chemists to create a variety of complex molecules with potential applications in various industries, such as pharmaceuticals, agrochemicals, and materials science.
Used in Chemical Research:
5,6-Dichloroindolin-2-one is used as a subject of study in chemical research to understand its reactivity, solubility, and safety profile. This information is crucial for determining its suitability and potential applications in different fields.

InChI:InChI=1/C8H5Cl2NO/c9-5-1-4-2-8(12)11-7(4)3-6(5)10/h1,3H,2H2,(H,11,12)

Upstream product

• 215959-21-0 2-(4,5-Dichloro-2-nitro-phenyl)-malonic acid diethyl ester 
• 286949-63-1 4,5-dichloro-2-nitrophenylacetic acid methyl ester 
• 37777-90-5 2-nitro-4,5-dichlorophenylacetic acid 
• 2339-78-8 1,2-dichloro-4-fluoro-5-nitrobenzene 

Downstream Products

• 286949-65-3 2,5,6-trichloroindole 
• 286949-66-4 2-bromo-5,6-dichloroindole 
• 1677-48-1 5,6-dichloroisatin 
• 286949-73-3 2-benzylthio-1-(2-deoxy-5-O-tert-butyldiphenylsilyl-3-O-mesyl-β-D-erythro-pentofuranosyl)-5,6-dichloroindole 
• 286949-67-5 2-benzylthio-1-[2-deoxy-3,5-bis-O-(4-methylbenzoyl)-β-D-erythro-pentofuranosyl]-5,6-dichloroindole 
• 286949-71-1 2-benzylthio-1-(2-deoxy-5-O-tert-butyldiphenylsilyl-β-D-erythro-pentofuranosyl)-5,6-dichloroindole 
• 286949-74-4 1-(2-deoxy-5-O-tert-butyldiphenylsilyl-3-O-mesyl-β-D-erythro-pentofuranosyl)-2,5,6-trichloroindole 
• 286949-68-6 1-[2-deoxy-3,5-bis-O-(4-methylbenzoyl)-β-D-erythro-pentofuranosyl]-2,5,6-trichloroindole 
• 286949-72-2 1-(2-deoxy-5-O-tert-butyldiphenylsilyl-β-D-erythro-pentofuranosyl)-2,5,6-trichloroindole 
• 286949-69-7 2-benzylthio-1-(2-deoxy-β-D-erythro-pentofuranosyl)-5,6-dichloroindole 
• 286949-75-5 2-benzylthio-5,6-dichloro-1-(2,3-dideoxy-β-D-glycero-pent-2-enofuranosyl)indole 
• 286949-64-2 2-benzylthio-5,6-dichloroindole 

Relevant academic research and scientific papers

Synthesis and antiviral evaluation of trisubstituted indole N- nucleosides as analogues of 2,5,6-Trichloro-1-(β-D- ribofuranosyl)benzimidazole (TCRB)

2,5,6-Trichloro-1-(β-D-ribofuranosyl)benzimidazole (TCRB) and 2-bromo- 5,6-dichloro-1-(β-D-ribofuranosyl)benzimidazole (BDCRB) are nucleosides that exhibit strong and selective activity against human cytomegalovirus (HCMV). Selected polyhalogenated indole

An improved procedure for the regiospecific synthesis of electron deficient 4- and 6-substituted isatins

The regiospecific synthesis of 4- and 6-substituted isatins 5a-g in four steps from halonitrobenzenes 1a-g has been investigated for a variety of substrates (Scheme 1). The procedure makes use of readily available, easily handled materials and in most cases purification of neither intermediates nor final products is required. Yields of isatins are between 26 and 75% (Table 1). Improved yields of known isatins are reported as well as the syntheses of previously unreported isatins. This method, taken together with known procedures, provides for the synthesis of the full complement of isatin regioisomers.

Oxindoles as sleep-inducers

Sleep inducers of the formula: STR1 wherein R is hydrogen or halo of atomic weight of from 18 to 36, R' is hydrogen, halo or CF3 and R° is hydrogen or lower alkyl. Preparation by cyclizing a 2-nitro-phenylacetic acid is also disclosed.