71293-59-9

Basic information

• Product Name: 5,6-DICHLOROINDOLIN-2-ONE
• Synonyms: 5,6-DICHLOROINDOLIN-2-ONE;5,6-Dichloro-2-oxindole;5,6-Dichloro-1,3-dihydro-2H-indol-2-one;5,6-dichloro-2,3-dihydro-1H-indol-2-one
• CAS NO: 71293-59-9
• Molecular Formula: C₈H₅Cl₂NO
• Molecular Weight: 202.04
• Product Categories: Indoline & Oxindole
• Mol File: 71293-59-9.mol
• Article Data: 3

Chemical Properties

• Melting Point: 209-210℃
• Boiling Point: 365.143 °C at 760 mmHg
• Flash Point: 174.633 °C
• Appearance: /
• Density: 1.497 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.615
• Storage Temp.: 2-8°C
• PKA: 12.19±0.20(Predicted)
• CAS DataBase Reference: 5,6-DICHLOROINDOLIN-2-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-DICHLOROINDOLIN-2-ONE(71293-59-9)
• EPA Substance Registry System: 5,6-DICHLOROINDOLIN-2-ONE(71293-59-9)

Safety Data

• Hazardous Substances Data: 71293-59-9(Hazardous Substances Data)

Usage

General Description

5,6-Dichloroindolin-2-one is a chemical compound categorized as an indolinone, which is an organic compound containing an indole substituted by a ketone. The structure of this compound includes a benzene fused to a pyrrolidine ring bearing two chlorine atoms and a ketone group. While there is limited information available on specific uses or properties of 5,6-dichloroindolin-2-one, indolinones in general are important in pharmacological research and are often used as building blocks in organic synthesis. Further information about its reactivity, solubility, or safety profile should be determined from specialized sources or professional chemical databases.

InChI:InChI=1/C8H5Cl2NO/c9-5-1-4-2-8(12)11-7(4)3-6(5)10/h1,3H,2H2,(H,11,12)

Upstream product

• 2339-78-8 1,2-dichloro-4-fluoro-5-nitrobenzene 
• 37777-90-5 2-nitro-4,5-dichlorophenylacetic acid 
• 286949-63-1 4,5-dichloro-2-nitrophenylacetic acid methyl ester 
• 215959-21-0 2-(4,5-Dichloro-2-nitro-phenyl)-malonic acid diethyl ester 

Downstream Products

• 1677-48-1 5,6-dichloroisatin 
• 286949-66-4 2-bromo-5,6-dichloroindole 
• 286949-65-3 2,5,6-trichloroindole 
• 286949-73-3 2-benzylthio-1-(2-deoxy-5-O-tert-butyldiphenylsilyl-3-O-mesyl-β-D-erythro-pentofuranosyl)-5,6-dichloroindole 
• 286949-67-5 2-benzylthio-1-[2-deoxy-3,5-bis-O-(4-methylbenzoyl)-β-D-erythro-pentofuranosyl]-5,6-dichloroindole 
• 286949-71-1 2-benzylthio-1-(2-deoxy-5-O-tert-butyldiphenylsilyl-β-D-erythro-pentofuranosyl)-5,6-dichloroindole 
• 286949-74-4 1-(2-deoxy-5-O-tert-butyldiphenylsilyl-3-O-mesyl-β-D-erythro-pentofuranosyl)-2,5,6-trichloroindole 
• 286949-68-6 1-[2-deoxy-3,5-bis-O-(4-methylbenzoyl)-β-D-erythro-pentofuranosyl]-2,5,6-trichloroindole 
• 286949-72-2 1-(2-deoxy-5-O-tert-butyldiphenylsilyl-β-D-erythro-pentofuranosyl)-2,5,6-trichloroindole 
• 286949-69-7 2-benzylthio-1-(2-deoxy-β-D-erythro-pentofuranosyl)-5,6-dichloroindole 
• 286949-75-5 2-benzylthio-5,6-dichloro-1-(2,3-dideoxy-β-D-glycero-pent-2-enofuranosyl)indole 
• 286949-64-2 2-benzylthio-5,6-dichloroindole 

Relevant articles and documents

Synthesis and antiviral evaluation of trisubstituted indole N- nucleosides as analogues of 2,5,6-Trichloro-1-(β-D- ribofuranosyl)benzimidazole (TCRB)

2,5,6-Trichloro-1-(β-D-ribofuranosyl)benzimidazole (TCRB) and 2-bromo- 5,6-dichloro-1-(β-D-ribofuranosyl)benzimidazole (BDCRB) are nucleosides that exhibit strong and selective activity against human cytomegalovirus (HCMV). Selected polyhalogenated indole

Oxindoles as sleep-inducers

Sleep inducers of the formula: STR1 wherein R is hydrogen or halo of atomic weight of from 18 to 36, R' is hydrogen, halo or CF3 and R° is hydrogen or lower alkyl. Preparation by cyclizing a 2-nitro-phenylacetic acid is also disclosed.