71307-26-1

Upstream product

• 91-56-5 indole-2,3-dione 
• 574-17-4 1-acetyl-1H-indole-2,3-dione 
• 1777-57-7 p-bromobenzoylmethylenetriphenylphosphorane 

Downstream Products

• 159867-42-2 3-[2-(4-bromophenyl)-2-oxoethylidene]-1,3-dihydroindol-2-one 
• 1361951-83-8 (3S,4'S,5'S)-tert-butyl 1-acetyl-4'-(4-bromobenzoyl)-5'-(3,5-dimethyl-1H-pyrazole-1-carbonyl)-2-oxo-2'-thioxospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate 
• 71307-28-3 9-acetyl-4-(4-bromo-benzoyl)-2-ethoxy-4,9-dihydro-pyrano[2,3-b]indole 
• 1455213-61-2 (2’R,3’S,4’S)-1-acetyl-2’-(4-bromobenzoyl)-4’-(2-oxo-1-phenylethyl)-2-oxo-1’-tosylspiro[indoline-3,3’-tetrahydroquinoline] 

Relevant academic research and scientific papers

Cinchona-based squaramide-catalysed cascade aza-Michael-Michael addition: Enantioselective construction of functionalized spirooxindole tetrahydroquinolines

An efficient enantioselective cascade aza-Michael-Michael addition reaction catalysed by a chiral bifunctional tertiary amine-squaramide catalyst has been developed. This cascade reaction proceeded well under mild conditions, furnishing highly functionalized spirooxindole tetrahydroquinolines with three contiguous stereocenters in excellent yields with excellent diastereoselectivities (>25:1 dr) and high enantioselectivities (up to 94% ee). The Royal Society of Chemistry 2013.

Core structure-based design of organocatalytic [3+2]-cycloaddition reactions: Highly efficient and stereocontrolled syntheses of 3,3′-pyrrolidonyl spirooxindoles

Extraordinary levels of stereocontrol were achieved in an efficient organocatalytic asymmetric [3+2]-cycloaddition reaction between an α-isothiocyanato imide and various methyleneindolinones. Simple precursors were used for the rapid construction of spiro