71346-17-3 Usage
Uses
Used in Pharmaceutical Development:
6-Fluorochromone-3-carboxylic acid 97 is used as a building block for the synthesis of novel drug molecules, particularly those with potential therapeutic applications. Its unique fluorinated structure and carboxylic acid functionality contribute to the development of new pharmaceutical compounds.
Used in Organic Chemistry Research:
6-Fluorochromone-3-carboxylic acid 97 is used as a precursor in the preparation of various fluorinated heterocyclic compounds with potential biological activities. This makes it a valuable tool in the field of organic chemistry for exploring new chemical reactions and synthesizing complex molecules.
Used in Laboratory Applications:
Due to its high purity of 97%, 6-Fluorochromone-3-carboxylic acid 97 is suitable for use in various laboratory applications, including the synthesis of new compounds, testing of chemical reactions, and as a reference material in analytical techniques.
Check Digit Verification of cas no
The CAS Registry Mumber 71346-17-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,3,4 and 6 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 71346-17:
(7*7)+(6*1)+(5*3)+(4*4)+(3*6)+(2*1)+(1*7)=113
113 % 10 = 3
So 71346-17-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H5FO4/c11-5-1-2-8-6(3-5)9(12)7(4-15-8)10(13)14/h1-4H,(H,13,14)
71346-17-3Relevant academic research and scientific papers
Synthesis and biological evaluation of chromone-3-carboxamides
Gordon, Allen T.,Ramaite, Isaiah D.I.,Mnyakeni-Moleele, Simon S.
, p. 148 - 160 (2021/01/20)
The aim of our study was to synthesize novel chromone-3-carboxamides and to conduct biological evaluations in search for lead compounds for the treatment of a range of debilitating disease states. Corresponding 2-hydroxyacetophenones were subjected to Vilsmeier-Haack formylation to give chromone-3-carbaldehydes, which were subsequently oxidised to give chromone-3-carboxylic acids. Treatment of the carboxylic acids with thionyl chloride resulted in the in situ formation of the corresponding acid chlorides, which were reacted with various amines in the presence of triethylamine to give the corresponding novel chromone-3-carboxamides in good yields. Selected chromone derivatives were then evaluated for their anti-inflammatory, anti-tryponosomal and cytotoxic properties.
