713518-77-5

Basic information

• Product Name: E-3-(4-phenoxy-quinazolin-6-yl)-acrylic acid methyl ester
• Synonyms: E-3-(4-phenoxy-quinazolin-6-yl)-acrylic acid methyl ester
• CAS NO: 713518-77-5
• Molecular Weight: 306.321
• Mol File: 713518-77-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: E-3-(4-phenoxy-quinazolin-6-yl)-acrylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: E-3-(4-phenoxy-quinazolin-6-yl)-acrylic acid methyl ester(713518-77-5)
• EPA Substance Registry System: E-3-(4-phenoxy-quinazolin-6-yl)-acrylic acid methyl ester(713518-77-5)

Safety Data

• Hazardous Substances Data: 713518-77-5(Hazardous Substances Data)

Upstream product

• 108-95-2 phenol 
• 139-02-6 sodium phenoxide 
• 287193-14-0 6-iodo-4-phenoxyquinazoline 
• 292638-85-8 acrylic acid methyl ester 

Downstream Products

• 916496-83-8 E-3-{4-[3-methyl-4-(6-methyl-pyridin-3-yloxy)-phenylamino]-quinazolin-6-yl}-acrylic acid methyl ester 

Relevant articles and documents

BICYCLIC DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH

The invention relates to substantially pure compounds of the formula (1): and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein R1, R2, R3, R5, and X are as defined herein, and wherein the compound of formula (1) optionally further comprises a hydroxy substituent, an O-glucuronic acid, or an N->O (N-oxide) moiety. The invention also relates to methods of treating abnormal cell growth in mammals by administering the compounds of formula (1) and to pharmaceutical compositions for treating such disorders that contain the compounds of formula (1). The invention also relates to methods of preparing the compounds of formula (1).