713528-27-9Relevant articles and documents
Synthesis, characterization and cytotoxicity of some palladium(II), platinum(II), rhodium(I) and iridium(I) complexes of ferrocenylpyridine and related ligands. Crystal and molecular structure of trans-dichlorobis(3-ferrocenylpyridine)palladium(II)
Rajput, Jaisheila,Moss, John R.,Hutton, Alan T.,Hendricks, Denver T.,Arendse, Catherine E.,Imrie, Christopher
, p. 1553 - 1568 (2004)
The preparation of a series of ferrocenyl nitrogen donor ligands including ferrocenylpyridines, ferrocenylphenylpyridines and 1,1′-di(2-pyridyl)ferrocene is described. Coordination studies of the substituted pyridines (L) were carried out with platinum, palladium, rhodium and iridium. This resulted in the preparation of the following types of complexes: [MCl(CO)2(L)] and [M(cod)(L)2]ClO4 where M=Rh or Ir, cod=1,5-cyclooctadiene; [M′Cl2(L 2] where M′=Pt or Pd. The X-ray crystal structure of trans -dichlorobis(3-ferrocenylpyridine)palladium was obtained. The complexes were screened for activity against two human cancer cell lines. At least two of the complexes displayed growth inhibition similar to that of the widely used chemotherapeutic agent, cis platin.
