714-72-7 Usage
Uses
Used in Pharmaceutical Industry:
(2,4-Dioxo-1,3-diazaspiro[4.4]non-3-yl)acetic acid is used as a potential pharmaceutical compound for its unique structural features. Its heterocyclic nature and the presence of carbonyl and carboxylic acid groups may offer opportunities for the development of new drugs with specific therapeutic applications.
Used in Chemical Research:
(2,4-Dioxo-1,3-diazaspiro[4.4]non-3-yl)acetic acid is used as a research compound in the field of organic chemistry. Its complex structure and the presence of multiple functional groups make it an interesting subject for studying chemical reactions, synthesis, and the exploration of new chemical properties.
Used in Material Science:
(2,4-Dioxo-1,3-diazaspiro[4.4]non-3-yl)acetic acid is used as a building block in the development of new materials. Its unique spirocyclic structure and functional groups may contribute to the creation of novel materials with specific properties, such as improved stability, reactivity, or selectivity in various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 714-72-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,1 and 4 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 714-72:
(5*7)+(4*1)+(3*4)+(2*7)+(1*2)=67
67 % 10 = 7
So 714-72-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H12N2O4/c12-6(13)5-11-7(14)9(10-8(11)15)3-1-2-4-9/h1-5H2,(H,10,15)(H,12,13)
714-72-7Relevant academic research and scientific papers
An Old Story in the Parallel Synthesis World: An Approach to Hydantoin Libraries
Bogolubsky, Andrey V.,Moroz, Yurii S.,Savych, Olena,Pipko, Sergey,Konovets, Angelika,Platonov, Maxim O.,Vasylchenko, Oleksandr V.,Hurmach, Vasyl V.,Grygorenko, Oleksandr O.
, p. 35 - 43 (2018/01/17)
An approach to the parallel synthesis of hydantoin libraries by reaction of in situ generated 2,2,2-trifluoroethylcarbamates and α-amino esters was developed. To demonstrate utility of the method, a library of 1158 hydantoins designed according to the lead-likeness criteria (MW 200-350, cLogP 1-3) was prepared. The success rate of the method was analyzed as a function of physicochemical parameters of the products, and it was found that the method can be considered as a tool for lead-oriented synthesis. A hydantoin-bearing submicromolar primary hit acting as an Aurora kinase A inhibitor was discovered with a combination of rational design, parallel synthesis using the procedures developed, in silico and in vitro screenings.
