71400-25-4

Upstream product

• 163301-92-6 N,N-dimethyl-N',N'-dimethoxyisophthaldiamide 
• 106-38-7 para-bromotoluene 
• 874-60-2 4-methyl-benzoyl chloride 
• 65844-89-5 1,3-bis-(trimethylstannyl)benzene 
• 5142-75-6 tri(p-tolyl)bismuth 
• 99-63-8 benzene-1,3-dicarbonyl dichloride 
• 108-88-3 toluene 

Downstream Products

• 1414888-81-5 C₃₇H₂₉N₂O₂⁽¹⁺⁾*Cl^(1-) 
• 1414888-87-1 C₃₆H₃₀N₂O₂ 
• 163301-93-7 4',4''-bis(bromomethyl)-1,3-dibenzoylbenzene 
• 597576-22-2 [3-(4-mercaptomethyl-benzoyl)-phenyl]-(4-mercaptomethyl-phenyl)-methanone 
• 40873-08-3 C₂₂H₁₂Cl₂O₄ 

Relevant academic research and scientific papers

A phosphane-free, atom-efficient cross-coupling reaction of triarylbismuths with acyl chlorides catalyzed by MCM-41-immobilized palladium complex

The first phosphane-free, heterogeneous, atom-efficient cross-coupling reaction of triarylbismuths and acyl chlorides was achieved in N-methylpyrrolidone (NMP) with Bu3N as the base at 80 °C in the presence of 1.5 mol-% MCM-41-immobilized bidentate nitrogen palladium complex [MCM-41-2N-Pd(OAc)2, MCM = mobile crystalline material] to yield a variety of unsymmetrical biaryl ketones in good to excellent yields. This heterogeneous palladium catalyst exhibited a high activity, which was similar to that of Pd(PPh3)4. The catalyst can be recovered by a simple filtration of the reaction solution and recycled in at least 10 consecutive trials without any decrease in activity. Our system not only avoids the use of phosphane ligands, but also solves the basic problem of palladium catalyst recovery and reuse. The first phosphane-free, heterogeneous, atom-efficient cross-coupling reaction of triarylbismuth compounds and acyl chlorides was achieved in N-methylpyrrolidone with Bu3N as the base at 80 °C in the presence of 1.5 mol-% MCM-41-immobilized bidentate nitrogen palladium complex [MCM-41-2N-Pd(OAc)2] to yield a variety of unsymmetrical biaryl ketones in good to excellent yields. Copyright

Preparation method of carbonyl functionalized type aromatic carboxylic acid

The invention discloses a preparation method of carbonyl functionalized type aromatic carboxylic acid. The preparation method comprises the following steps of enabling aromatic acid halide and methylbenzene to generate Friedel-Crafts reaction to produce a

Design and synthesis of novel chiral dihydroimidazolium cyclophanes as N-heterocyclic carbene precatalysts

A series of novel diphenyl ethylenediamine (DPEN) derived C2 symmetric dihydroimidazolium cyclophanes were designed and synthesized as organo NHC precatalysts. The resultant organo NHC-catalyzed reactions with superior enantioselectivity than t

Design and synthesis of novel chiral dihydroimidazolium cyclophanes as N-heterocyclic carbene precatalysts

A series of novel diphenyl ethylenediamine (DPEN) derived C2 symmetric dihydroimidazolium cyclophanes were designed and synthesized as organo NHC precatalysts. The resultant organo NHC-catalyzed reactions with superior enantioselectivity than t

Efficient catalyst-free bi- and triaroylation of aromatic rings in a single step

(Chemical Equation Presented) The exceptional leaving group ability of the trimethylstannyl group in electrophilic aromatic substitutions makes possible the synthesis, in a single step, of bi- and triaroylarenes through the catalyst-free, regioselective reaction of bi- and tristannylarenes with different aroyl halides in o-dichlorobenzene as solvent. Specific di- and triketones are obtained in good to excellent yields (45-83%).

Atom-efficient cross-coupling reactions of triarylbismuths with acyl chlorides under Pd(0) catalysis

The atom-efficient cross-coupling reaction of triarylbismuths with a variety of aliphatic, aromatic, and hetero-aromatic acyl chlorides was demonstrated to afford high yields of cross-coupled ketones under palladium catalysis. The corresponding cross-coupling reaction with diacid chlorides also furnished bis-coupled ketones in good yields.

Synthesis of annularly functionalized cyclophanes

Friedel-Crafts reaction of m- and p-benzenedicarboxylic acid chlorides with toluene gave diketones. The dicarbonyl dibromides, obtained by NBS bromination of diketones were coupled with various dithiols and dihydroxy benzenes to give cyclophanes incorpora

Synthesis of chiral cyclophanes based on meta-terphenyl and pyridyl blocks

Coupling of m-terphenyl dibromide with binol afforded the corresponding optically active cyclophane. Chiral cyclophanes were also obtained by the coupling of p-nitrophenol or 4,4″-bis(bromomethyl)-1,3-dibenzylbenzene with binol.

Bisoxadiazolidine derivative

A bisoxadiazolidine dione derivative represented by the following general formula (I) or a pharmaceutically acceptable salt thereof, which is useful as an insulin sensitivity-increasing drug, and a pharmaceutical composition thereof. STR1 each represents a phenylene group L: (1) an oxygen, (2) a STR2 (3) a --S(O)n --, (4) a --CO--, (5) a STR3 (6) an alkylene group or an alkenylene group which may respectively be interrupted with an oxygen atom and/or a sulfur atom.

Process of preparation of ketones

Process of preparation of ketones by the reaction of an organo-metallic compound with a compound carrying a carbonyl, within a solvent, in the presence of a manganous salt as catalyst. The manganous salt is in the form of a double salt of Mn and an alkali metal cation.