71403-19-5

Basic information

• Product Name: Phosphine, [1,4-phenylenebis(methylene)]bis[diphenyl-
• CAS NO: 71403-19-5
• Molecular Formula: C32H28P2
• Molecular Weight: 474.522
• Mol File: 71403-19-5.mol

Chemical Properties

• CAS DataBase Reference: Phosphine, [1,4-phenylenebis(methylene)]bis[diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphine, [1,4-phenylenebis(methylene)]bis[diphenyl-(71403-19-5)
• EPA Substance Registry System: Phosphine, [1,4-phenylenebis(methylene)]bis[diphenyl-(71403-19-5)

Safety Data

• Hazardous Substances Data: 71403-19-5(Hazardous Substances Data)

Usage

Uses

Used in Organometallic Chemistry:
Triphenylphosphine is used as a ligand in organometallic chemistry for the formation of metal complexes. Its ability to coordinate with metal ions enhances the stability and reactivity of these complexes, making them suitable for various applications in catalysis and materials science.
Used in Reducing Agents:
Triphenylphosphine serves as a reducing agent in various chemical reactions, including the reduction of carbonyl compounds, nitro groups, and halides. Its strong electron-donating ability facilitates the transfer of electrons, leading to the formation of the desired products.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, triphenylphosphine is utilized in the synthesis of various drugs and active pharmaceutical ingredients. Its ability to act as a ligand or reducing agent aids in the formation of complex molecular structures, contributing to the development of novel therapeutic agents.
Used in Polymer Synthesis:
Triphenylphosphine is employed in the synthesis of polymers, particularly in the preparation of conductive polymers and polymers with specific functional groups. Its coordination properties enable the formation of polymers with tailored properties, such as electrical conductivity, stability, and reactivity.
Used in Organic Synthesis:
In organic synthesis, triphenylphosphine is used as a reagent or catalyst in various reactions, including cross-coupling reactions, cyclization reactions, and the formation of carbon-carbon bonds. Its ability to stabilize intermediates and facilitate electron transfer enhances the efficiency and selectivity of these reactions.
Safety Precautions:
It is important to handle triphenylphosphine with caution, as it can be harmful if inhaled or ingested and may cause skin and eye irritation. Proper safety measures, such as wearing protective clothing and using appropriate ventilation, should be taken during its use to minimize potential health risks.

Upstream product

• 623-24-5 1,4-bis(bromomethyl)benzene 
• 65567-06-8 lithium diphenylphosphide 
• 1079-66-9 chloro-diphenylphosphine 
• 829-85-6 diphenylphosphane 

Downstream Products

• 169782-92-7 (1,4-bis(diphenylphosphanylmethyl)benzene)-μ-phenylsulfoniumdigold(I) tetrafluoroborate 
• 169782-94-9 (1,4-bis(diphenylphosphanylmethyl)benzene)-μ-methylsulfoniumdigold(I) tetrafluoroborate 
• 169782-90-5 (1,4-bis(diphenylphosphanylmethyl)benzene)-μ-chloroniumdigold(I) tetrafluoroborate 
• 169782-88-1 (1,4-bis(diphenylphosphanylmethyl)benzene)bismethanethiolatogold(I) 
• 169782-95-0 (1,4-bis(diphenylphosphanylmethyl)benzene)-μ-sulfoniumdigold(I) 
• 87370-06-7 2,2,2-carbonylbis(triphenylphosphine)-nido-2-osmapentaborane 
• 169782-87-0 [α,α'-bis(diphenylphosphino)-p-xylene]bis[chlorogold] 
• 252032-16-9 [(α,α'-bis(diphenylphosphino)-p-xylene)*Ru(p-cymene)Cl2] 
• 38661-56-2 (1,4-phenylenebis(methylene))bis(diphenylphosphine oxide) 

Relevant articles and documents

Palladium(II) and copper(I) complexes of wide angle bisphosphine, 1,4-bis((diphenylphosphino)methyl)benzene

Abstract : Oxidation reactions and synthesis of copper(I) and palladium(II) complexes of 1,4-bis((diphenylphosphino)methyl)benzene (1) have been described. Due to the larger separation of phosphorus atoms, bisphosphine exhibits only bridging mode of coord

Using polarization effects to alter chemical reactivity: A simple host which enhances amine nucleophilicity

(Matrix Presented) The rational design of a bis(phosphine oxide) host which is capable of binding a benzylic amine is presented. The ability of this host to increase the rate of addition of 4-fluorobenzylamine to N-phenylmaleimide is rationalized in terms of the enhancement of the nucleophilicity of the benzylic amine.

Platinum Chloride-Diphosphine-Tin(II) Halide Systems as Active and Selective Hydroformylation Catalysts

The hydroformylation of 1-alkenes was efficiently catalyzed by PtCl2-diphosphine-SnX2 systems whose diphosphines were 1,4-bis(diphenylphosphino)butane derivatives with rigid ring skeletons.The effects of the structure of diphosphines, the P/Pt atomic ratio, the sort of tin(II) halide or solvent, the reaction variables, and the structure of olefins on the relative rate and the product distribution were investigated.A higher reaction rate than when using HRh(CO)(PPh3)3, and a linearity of aldehydes up to 99percent, were attained.The coordination structure of the effective diphosphines as well as the reasons for the rate enhancement and for the excellent selectivity were discussed.