71410-73-6

Basic information

• Product Name: 5,10-di(4-pyridyl)-15,20-diphenylporphyrin
• Synonyms: 5,10-Diphenyl-15,20-di(4-pyridyl)-21H,23H-porphine;5,10-di(4-pyridyl)-15,20-diphenylporphyrin;21H,23H-Porphine, 5,10-diphenyl-15,20-di-4-pyridinyl-
• CAS NO: 71410-73-6
• Molecular Formula: C₄₂H₂₈N₆
• Molecular Weight: 616.71192
• Mol File: 71410-73-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5,10-di(4-pyridyl)-15,20-diphenylporphyrin(CAS DataBase Reference)
• NIST Chemistry Reference: 5,10-di(4-pyridyl)-15,20-diphenylporphyrin(71410-73-6)
• EPA Substance Registry System: 5,10-di(4-pyridyl)-15,20-diphenylporphyrin(71410-73-6)

Safety Data

• Hazardous Substances Data: 71410-73-6(Hazardous Substances Data)

Upstream product

• 872-85-5 pyridine-4-carbaldehyde 
• 109-97-7 pyrrole 
• 100-52-7 benzaldehyde 

Downstream Products

• 138942-65-1 C₉₂H₇₀N₁₀⁽²⁺⁾*2I^(1-) 
• 138942-68-4 C₁₄₀H₁₁₀N₁₆⁽⁴⁺⁾*4I^(1-) 

Relevant articles and documents

A Discrete Platinum(II) Amphiphile: Construction, Characterization, and Controllable Self-Assembly in Different Solvents

Coordination-driven self-assembly offers us an efficient method to fabricate 3D metallacages and 2D metallacycles with controllable shape and size via simple building blocks. Herein, a new discrete platinum(II) amphiphile (AOM), which contains hydrophilic tris(ethylene oxide) chains and a hydrophobic porphyrin unit, was constructed successfully by using coordination-driven self-assembly . From various characterization methods, such as UV-vis spectroscopy, dynamic light scattering, transmission electron microscopy, scanning electron microscopy, and small-angle X-ray scattering, we found that AOM can self-assemble into vesicles, curved vesicles with open ends, and at last stable bilayer nanotubes in aqueous solution at room temperature and flexible cross-linked structures at about 60 °C. In contrast, AOM formed rigid bilayer nanosheets of micrometers in width and millimeters in length in n-hexane. We hope this investigation will pave the way for the fabrication of controllable soft materials.

Photodynamic effect of meso-(aryl)porphyrins and meso-(1-methyl-4-pyridinium)porphyrins on HaCaT keratinocytes

Sixteen porphyrins, including neutral, anionic and cationic meso-(aryl)porphyrins and meso-(1-methyl-4-pyridinium)porphyrins were herein evaluated in terms of their photosensitizing properties against HaCaT keratinocytes. After an initial screening, the cationic porphyrins were studied in more details, by both determining their log POWand performing PDT assays in lower porphyrin concentrations. Porphyrins presenting two or more adjacent positively charged groups, directly linked to the macrocycle meso positions, appeared to be the most effective photosensitizers. The present study also included the dicationic 5,10-diphenyl-15,20-di(1-methylpyridinium-4-yl)porphyrin (14b), which has previously shown promising results on a psoriasis-like in vivo model. Overall results indicated that the beneficial effect related to porphyrins on psoriasis can be related to the decreasing of keratinocyte viability. Furthermore, some of the cationic porphyrins studied appeared as candidates to be utilized as photosensitizers for psoriasis treatment.