714264-84-3Relevant academic research and scientific papers
Synthesis of OSW-1 analogs with modified side chains and their antitumor activities
Deng, Lehua,Wu, Hao,Yu, Biao,Jiang, Manrong,Wu, Jiarui
, p. 2781 - 2785 (2004)
Four analogs of OSW-1 (1-4) with modified side chains on the steroidal skeleton were synthesized following modification of our previous route for the total synthesis of OSW-1. Testing of the analogs against growth of tumor cells demonstrated that the 22-one function and the full length of the side chain of OSW-1 were not required for the antitumor action of OSW-1.
