71432-53-6 Usage
Uses
Used in Organic Synthesis:
[2-(1-methylethyl)phenoxy]acetonitrile is used as a versatile building block for the synthesis of various organic compounds due to its unique structure and functional groups.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, [2-(1-methylethyl)phenoxy]acetonitrile is used as an intermediate in the production of various pharmaceuticals, contributing to the development of new drugs and therapies.
Used in Agricultural Chemicals:
[2-(1-methylethyl)phenoxy]acetonitrile is also utilized as an intermediate in the production of pesticides and other agricultural chemicals, playing a crucial role in the development of effective and safe products for crop protection and management.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, [2-(1-methylethyl)phenoxy]acetonitrile serves as an important intermediate for the synthesis of various drug candidates, aiding in the advancement of pharmaceutical research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 71432-53-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,4,3 and 2 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 71432-53:
(7*7)+(6*1)+(5*4)+(4*3)+(3*2)+(2*5)+(1*3)=106
106 % 10 = 6
So 71432-53-6 is a valid CAS Registry Number.
InChI:InChI=1/C11H13NO/c1-9(2)10-5-3-4-6-11(10)13-8-7-12/h3-6,9H,8H2,1-2H3
71432-53-6Relevant academic research and scientific papers
Identification and SAR of novel diaminopyrimidines. Part 1: The discovery of RO-4, a dual P2X3/P2X2/3 antagonist for the treatment of pain
Carter, David S.,Alam, Muzaffar,Cai, Haiying,Dillon, Michael P.,Ford, Anthony P.D.W.,Gever, Joel R.,Jahangir, Alam,Lin, Clara,Moore, Amy G.,Wagner, Paul J.,Zhai, Yansheng
scheme or table, p. 1628 - 1631 (2009/11/30)
P2X purinoceptors are ligand-gated ion channels whose endogenous ligand is ATP. Both the P2X3 and P2X2/3 receptor subtypes have been shown to play an important role in the regulation of sensory function and dual P2X3/P2X2/3 antagonists offer significant potential for the treatment of pain. A high-throughput screen of the Roche compound collection resulted in the identification of a novel series of diaminopyrimidines; subsequent optimization resulted in the discovery of RO-4, a potent, selective and drug-like dual P2X3/P2X2/3 antagonist.
