71432-53-6 Usage
General Description
"[2-(1-methylethyl)phenoxy]acetonitrile" is a chemical compound with the molecular formula C11H13NO. It is a nitrile derivative and contains a phenoxy functional group along with an isopropyl group attached to the carbon atom. [2-(1-methylethyl)phenoxy]acetonitrile is commonly used in the synthesis of various organic compounds and pharmaceuticals. It is also known for its use as an intermediate in the production of pesticides and other agricultural chemicals. The presence of the nitrile group in its structure makes it a versatile building block for the preparation of various organic molecules and it is often employed in organic synthesis and medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 71432-53-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,4,3 and 2 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 71432-53:
(7*7)+(6*1)+(5*4)+(4*3)+(3*2)+(2*5)+(1*3)=106
106 % 10 = 6
So 71432-53-6 is a valid CAS Registry Number.
InChI:InChI=1/C11H13NO/c1-9(2)10-5-3-4-6-11(10)13-8-7-12/h3-6,9H,8H2,1-2H3
71432-53-6Relevant articles and documents
Identification and SAR of novel diaminopyrimidines. Part 1: The discovery of RO-4, a dual P2X3/P2X2/3 antagonist for the treatment of pain
Carter, David S.,Alam, Muzaffar,Cai, Haiying,Dillon, Michael P.,Ford, Anthony P.D.W.,Gever, Joel R.,Jahangir, Alam,Lin, Clara,Moore, Amy G.,Wagner, Paul J.,Zhai, Yansheng
scheme or table, p. 1628 - 1631 (2009/11/30)
P2X purinoceptors are ligand-gated ion channels whose endogenous ligand is ATP. Both the P2X3 and P2X2/3 receptor subtypes have been shown to play an important role in the regulation of sensory function and dual P2X3/P2X2/3 antagonists offer significant potential for the treatment of pain. A high-throughput screen of the Roche compound collection resulted in the identification of a novel series of diaminopyrimidines; subsequent optimization resulted in the discovery of RO-4, a potent, selective and drug-like dual P2X3/P2X2/3 antagonist.
