71445-76-6Relevant academic research and scientific papers
Iron-catalyzed allylic arylation of olefins via C(sp3)-H activation under mild conditions
Sekine, Masaki,Ilies, Laurean,Nakamura, Eiichi
supporting information, p. 714 - 717 (2013/04/10)
An aryl Grignard reagent in the presence of mesityl iodide converts an allylic C-H bond of a cycloalkene or an allylbenzene derivative into a C-C bond in the presence of a catalytic amount of Fe(acac)3 and a diphosphine ligand at 0 C. The stereo- and regioselectivity of the reaction, together with deuterium labeling experiments, suggest that C-H bond activation is the slow step in the catalytic cycle preceding the formation of an allyliron intermediate.
