71448-05-0Relevant academic research and scientific papers
Reactivity of Tyrosyl–Proline toward Benzoylation in Aqueous 1,4-Dioxane
Khachatryan, D. S.,Kochetova, L. B.,Kustova, T. P.,Lokteva, I. I.
, p. 1034 - 1040 (2020/07/25)
Abstract: The kinetics of the reaction of L-tyrosyl-L-proline (Tyr–Pro) with di- andtrinitrophenyl benzoates in aqueous 1,4-dioxane (40 wt percent of water) were studiedin the temperature range 298–313 K. The reaction rate constant k298 was fou
Catalytic, one-pot synthesis of β-amino acids from α-amino acids. Preparation of α,β-peptide derivatives
Saavedra, Carlos,Hernandez, Rosendo,Boto, Alicia,Alvarez, Eleuterio
supporting information; experimental part, p. 4655 - 4665 (2009/10/09)
(Chemical Equation Presented) The one-pot conversion of readily available α-amino acid into β-amino acid derivatives was carried out in good yields. The method is a sequential process initiated by a tandem radical decarboxylation-oxidation reaction; the resulting acyliminium ion was trapped by silyl ketenes. Stoichiometric and catalytic versions of this reaction were developed and then applied to prepare modified di- and tripeptides. Interestingly, some tripeptides formed expanded β-turns in the solid state.
Reactivity of the Amino Groups of α-Amino Acids and Dipeptides in Reaction with Benzoyl Chloride in a Dioxane-Water Solvent
Kuritsyn, L. V.,Kalinina, N. V.
, p. 767 - 770 (2007/10/02)
The kinetic characteristics (rate constants, activation energies, and entropies of activation) for the reaction of a series of α-amino acids and dipeptides with benzoyl chloride in aqueous dioxane are presented.The amino group in the investigated α-amino acids has high reactivity 4 liter/mole*sec>; the dipeptides have lower reactivity 3 liter/mole*sec>.
