71448-29-8

Usage

Uses

suzuki reaction

InChI:InChI=1/C17H33NO3/c1-3-4-5-6-7-8-9-10-11-12-13-14-16(19)18-15(2)17(20)21/h15H,3-14H2,1-2H3,(H,18,19)(H,20,21)/t15-/m0/s1

Upstream product

• 56-41-7 L-alanin 
• 112-64-1 tetradecanoyl chloride 
• 338-69-2 D-Alanine 
• 2425-54-9 myristyl chloride 

Downstream Products

• 1480504-45-7 Myristoyl-Ala-Met-Arg-Pro-Tyr-Asp-Ala-Asn-Lys-Arg-NH₂ 

Relevant academic research and scientific papers

COMPOUNDS USEFUL IN HIV THERAPY

The invention relates to compounds of Formula (I), salts thereof, pharmaceutical compositions thereof, as well as methods of treating or preventing HIV in subjects.

Integrating CuInSe2nanocrystals with polymeric carbon nitride nanorods for photocatalytic water splitting

Developing photocatalysts with improved photoactivity and efficiency has remained an enduring theme both fundamentally and technologically in the field of photocatalysis. Polymeric carbon nitride (CN) has been widely exploited as an earth-abundant photocatalyst for water redox reactions. Nevertheless, the limited visible-light utilization rate and the high recombination rate of photoinduced charge carriers give rise to the moderate photocatalytic reactivity of CN in water splitting. Herein, p-type CuInSe2nanocrystals are prepared by a solvothermal approach and then immobilized with n-type CN nanorods through self-assembly and thermal treatment process, forming a CuInSe2/CN hybrid photocatalyst. Benefiting from the p-n heterojunction, a 3% CuInSe2/CN nanocomposite photocatalyst exhibits a three-fold increase in the hydrogen evolution rate (HER) compared to that of bare CN nanorods owing to the strengthened visible-light capturing capability and improved separation rate of photoexcited charge carriers. This work paves new avenues for the construction of p-n heterojunction photocatalysts for solar fuel production.

A modular approach towards drug delivery vehicles using oxanorbornane-based non-ionic amphiphiles

The self-assembly of non-ionic amphiphiles with a hydroxylated oxanorbornane head-group was controlled using amino acid units as spacers between hydrophilic and lipophilic domains to get spherical supramolecular aggregates. The ability of these systems to harbour therapeutic agents like ibuprofen, and their drug-release profiles were evaluated. Apart from directing the assembly, the intervening amino acid unit was found to help in drug entrapment as well. The presence of cholesterol improved their drug-loading ability, and an encapsulation efficiency of up to 66% was shown by the formulation containing the phenylalanine residue as the spacer (NC1c). There was no burst release, and 45% drug release was observed at the end of 24 h in this case (cf. soyaphosphatidylcholine based formulation = 49%). The results from SEM, Cryo-TEM, PXRD and confocal microscopic studies with some insights into molecular packing in this class of aggregates are also included.

Molecular mechanism of physical gelation of hydrocarbons by fatty acid amides of natural amino acids

A variety of fatty acid amides of different naturally occurring l-amino acids have been synthesized and they are found to form gels with various hydrocarbons. The gelation properties of these compounds were studied by a number of physical methods including FTIR spectroscopy, X-ray diffraction, scanning electron microscopy, differential scanning calorimetry, rheology, and it was found that gelation depended critically on the fatty acid chain length and the nature of the amino acid. Among them l-alanine based gelators were found to be the most efficient and versatile gelators as they self-assemble into a layered structure to form the gel network. Mechanisms for the assembly and formation of gels from these molecules are discussed.

Self-assembled organogels formed by mono-chain L-alanine derivatives

The mono-chain L-alanine derivatives self-assemble into bilayer aggregates in a number of organic liquids and gelatinize the liquids.